{"title":"同时进行肝脏和肾脏移植手术后的掩蔽性肾脏同种异体移植失败:病例报告","authors":"Kasra Shirini , Ujwal Gautam , Hiba Ahmed , Raphael P.H. Meier , Cinthia Drachenberg , Abdolreza Haririan","doi":"10.1016/j.liver.2024.100237","DOIUrl":null,"url":null,"abstract":"<div><p>Kidney utilization for simultaneous liver-kidney transplantation (SLK) has seen a significant increase in recent years, driven by the rising prevalence of renal dysfunction among liver transplant candidates. However, a substantial proportion of SLK recipients experience native kidney function recovery post-transplant, rendering the kidney transplant unnecessary. This case report presents a remarkable instance of native renal function recovery in a SLK recipient, discovered eleven years after transplantation, when the transplanted kidney was found to have undergone extensive fibrosis and atrophy, masked by native kidney recovery. This case highlights the challenges posed by evaluation of SLK candidates and the need for improved tools to predict native kidney recovery. Safety net mechanism for those who do not recover kidney function should be utilized more to avoid the unnecessary utilization of scarce kidney allografts, which are critically needed for waitlisted patients with kidney failure.</p></div>","PeriodicalId":100799,"journal":{"name":"Journal of Liver Transplantation","volume":"16 ","pages":"Article 100237"},"PeriodicalIF":0.0000,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666967624000382/pdfft?md5=9d9e835379b1ff1d8263f3cf175d087d&pid=1-s2.0-S2666967624000382-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Masked kidney allograft failure after simultaneous liver and kidney transplantation: A case report\",\"authors\":\"Kasra Shirini , Ujwal Gautam , Hiba Ahmed , Raphael P.H. Meier , Cinthia Drachenberg , Abdolreza Haririan\",\"doi\":\"10.1016/j.liver.2024.100237\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Kidney utilization for simultaneous liver-kidney transplantation (SLK) has seen a significant increase in recent years, driven by the rising prevalence of renal dysfunction among liver transplant candidates. However, a substantial proportion of SLK recipients experience native kidney function recovery post-transplant, rendering the kidney transplant unnecessary. This case report presents a remarkable instance of native renal function recovery in a SLK recipient, discovered eleven years after transplantation, when the transplanted kidney was found to have undergone extensive fibrosis and atrophy, masked by native kidney recovery. This case highlights the challenges posed by evaluation of SLK candidates and the need for improved tools to predict native kidney recovery. Safety net mechanism for those who do not recover kidney function should be utilized more to avoid the unnecessary utilization of scarce kidney allografts, which are critically needed for waitlisted patients with kidney failure.</p></div>\",\"PeriodicalId\":100799,\"journal\":{\"name\":\"Journal of Liver Transplantation\",\"volume\":\"16 \",\"pages\":\"Article 100237\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666967624000382/pdfft?md5=9d9e835379b1ff1d8263f3cf175d087d&pid=1-s2.0-S2666967624000382-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Liver Transplantation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666967624000382\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Liver Transplantation","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666967624000382","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Masked kidney allograft failure after simultaneous liver and kidney transplantation: A case report
Kidney utilization for simultaneous liver-kidney transplantation (SLK) has seen a significant increase in recent years, driven by the rising prevalence of renal dysfunction among liver transplant candidates. However, a substantial proportion of SLK recipients experience native kidney function recovery post-transplant, rendering the kidney transplant unnecessary. This case report presents a remarkable instance of native renal function recovery in a SLK recipient, discovered eleven years after transplantation, when the transplanted kidney was found to have undergone extensive fibrosis and atrophy, masked by native kidney recovery. This case highlights the challenges posed by evaluation of SLK candidates and the need for improved tools to predict native kidney recovery. Safety net mechanism for those who do not recover kidney function should be utilized more to avoid the unnecessary utilization of scarce kidney allografts, which are critically needed for waitlisted patients with kidney failure.