随机对照试验,调查多模式移动应用治疗慢性疼痛的效果。

IF 2 Q3 CLINICAL NEUROLOGY
Cynthia J Thomson, Hanna Pahl, Luisa V Giles
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引用次数: 0

摘要

背景:直到最近,慢性疼痛的治疗通常依赖于面对面的干预,尽管如今有了更多的混合护理选择,但提供服务的能力仍然面临挑战。侧重于疼痛的社会心理方面的数字程序可能会提供低门槛的替代方案。目的:通过随机对照试验,我们研究了多模式移动应用程序的有效性:患有非恶性慢性疼痛的参与者(n = 198;82% 为女性,平均年龄 = 46.7 [13.1] 岁;平均疼痛持续时间为 13.6 [11.2] 年)被随机分配到为期 6 周的干预组(n = 98)或候补常规护理组(n = 100)。干预措施包括定期使用由用户指导的移动应用程序(Curable Inc.)共同主要结果为 6 周后的疼痛严重程度和干扰程度:我们观察到,与对照组相比,干预组的疼痛严重程度和干扰程度有明显改善,估计变化分别为-0.67(95% 置信区间 [CI] -1.04 至 -0.29,P d = 0.43)和-0.60(95% CI -1.18 至 -0.03,P = .04,d = 0.27)。次要结果(患者报告结果测量信息系统疼痛干扰;疼痛灾难化;焦虑、抑郁;压力)均有明显改善。应用程序的使用频率与疼痛干扰的改善相关(P = 0.018),干预组在 12 周后仍能保持与基线相比的变化(P 结论:与等待名单上的常规护理相比,短期移动应用程序干预显著改善了身心健康结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Randomized controlled trial investigating the effectiveness of a multimodal mobile application for the treatment of chronic pain.

Background: Until recently, treatments for chronic pain commonly relied on in-person interventions, and despite more hybrid care options today, capacity for delivery remains challenged. Digital programs focusing on the psychosocial aspects of pain may provide low-barrier alternatives.

Aims: Through a randomized controlled trial, we investigated the effectiveness of a multimodal mobile application.

Methods: Participants (n = 198; 82% women, mean age = 46.7 [13.1] years; mean pain duration 13.6 [11.2] years) with nonmalignant chronic pain were randomized to either a 6-week intervention (n = 98) or a wait-listed usual care group (n = 100). The intervention involved regular engagement with a user-guided mobile application (Curable Inc.) informed by the biopsychosocial model of pain that included pain education, meditation, cognitive behavioral therapy, and expressive writing. The co-primary outcomes were pain severity and interference at 6 weeks.

Results: We observed significant improvements in the intervention group compared to the control group with estimated changes of -0.67 (95% confidence interval [CI] -1.04 to -0.29, P < .001, d = 0.43) and -0.60 (95% CI -1.18 to -0.03, P = .04, d = 0.27) for pain severity and interference, respectively. There were significant improvements across secondary outcomes (Patient-Reported Outcome Measurement Information System pain interference; pain catastrophizing; anxiety, depression; stress). Frequency of app use was correlated with improved pain interference (P < .001) and pain catastrophizing (P = 0.018), and changes from baseline persisted in the intervention group at 12 weeks (P < .05).

Conclusions: A short-term mobile app intervention resulted in significant improvements across physical and mental health outcomes compared to wait-listed usual care.

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来源期刊
CiteScore
3.70
自引率
12.50%
发文量
36
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