纯前向与逆行慢性全闭塞经皮冠状动脉介入治疗后的疗效:CCTOP 登记的启示。

IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Louis Verreault-Julien, Israth Jahan, Nandini Dendukuri, Luiz F Ybarra, Samer Mansour, Alexis Matteau, Harindra C Wijeysundera, Anthony Fung, Simon Robinson, Jean-Michel Paradis, Can Manh Nguyen, Stéphane Rinfret
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引用次数: 0

摘要

背景:慢性全闭塞(CTO)经皮冠状动脉介入治疗(PCI)可采用纯前向途径(AO)或逆行途径(RA)。RA是否会带来更高的并发症风险需要进一步研究:加拿大 CTO PCI(CCTOP)是一项由研究者发起的多中心、前瞻性队列研究,于 2014 年 3 月至 2019 年 10 月期间在加拿大 6 个经验丰富的中心进行。接受RA的患者与接受AO的患者进行了比较。主要终点是院内主要心脏不良事件(MACE),定义为死亡、PCI后任何心肌酶升高、紧急血管再通术和填塞。为控制潜在的混杂因素,进行了多变量分析:研究共纳入了 1033 例患者,48.4% 的病例使用了 RA。RA与较高的病变复杂性(J-CTO评分为2.7 ± 1.1 vs 2.3 ± 1.1,P < .001)和较低的技术成功率(81.2% vs 91.5%,P < .001)相关。RA组发生院内MACE的风险更高(10.2% vs 4.7%,P < .001),所有死亡病例均发生在RA组(0.8% vs 0%,P = .038)。在多变量模型中,RA 仍与 MACE 风险增加相关(OR,2.25;95% CI,1.26 至 4.02):我们的经验证实,与AO方法相比,RA与院内MACE风险增加有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes following antegrade-only versus retrograde chronic total occlusion percutaneous coronary intervention: insights from the CCTOP registry.
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来源期刊
Journal of Invasive Cardiology
Journal of Invasive Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.90
自引率
6.70%
发文量
214
审稿时长
3-8 weeks
期刊介绍: The Journal of Invasive Cardiology will consider for publication suitable articles on topics pertaining to the invasive treatment of patients with cardiovascular disease.
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