利用基于变换的函数和机器学习算法,实现高灵敏度的高精度脑肿瘤检测。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Ashish Bhatt, Vineeta Saxena Nigam
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引用次数: 0

摘要

背景:脑肿瘤是一种极其危险的疾病,在全球范围内死亡率极高。由于肿瘤细胞的外观各不相同,其生长的维度也不规则,因此准确检测脑肿瘤至关重要。这给检测算法带来了巨大挑战。目前,有许多算法可用于这一目的,从基于变换的方法到植根于机器学习技术的算法,不一而足。这些算法旨在提高检测的准确性,尽管在识别脑肿瘤细胞方面存在复杂性。这些算法的主要局限是将提取的脑肿瘤特征映射到分类算法中:采用组合变换方法从脑肿瘤图像中提取纹理特征:本文采用了基于子带分解的变换方法组合来提取核磁共振成像扫描图像的纹理特征,使用萤火虫和萤火虫算法的混合特征优化方法来选择特征,采用 MKSVM 算法和堆叠集合分类器来进行分类,并应用不同特征提取方法的融合特征:使用 MATLAB,利用 2013 年、2015 年和 2018 年的 BRATS(脑肿瘤分割)数据集,将所考虑的算法付诸实践。这些数据集是测试和验证算法在不同时期性能的基础,可全面评估算法在检测脑肿瘤方面的有效性。所提出的算法实现了最高检测准确率、检测灵敏度和特异性,分别高达 98%、99% 和 99.5%。实验结果展示了该算法在检测脑肿瘤方面的效率:本文主要从以下几个方面对脑肿瘤检测做出了贡献:a) 使用组合变换方法从核磁共振扫描图像中提取纹理特征;b) 使用萤火虫和萤火虫优化算法的混合特征选择方法进行特征选择;c) 使用 MKSVM 算法和堆叠集合分类器进行分类,并应用不同特征提取方法的融合特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Highly accurate brain tumor detection with high sensitivity using transform-based functions and machine learning algorithms.

Background: Brain tumor is an extremely dangerous disease with a very high mortality rate worldwide. Detecting brain tumors accurately is crucial due to the varying appearance of tumor cells and the dimensional irregularities in their growth. This poses a significant challenge for detection algorithms. Currently, there are numerous algorithms utilized for this purpose, ranging from transform-based methods to those rooted in machine learning techniques. These algorithms aim to enhance the accuracy of detection despite the complexities involved in identifying brain tumor cells. The major limitation of these algorithms is the mapping of extracted features of a brain tumor in the classification algorithms.

Objective: To employ a combination of transform methods to extract texture feature from brain tumor images.

Methods: This paper employs a combination of transform methods based on sub band decomposition for texture feature extraction from MRI scans, hybrid feature optimization methods using firefly and glow-worm algorithms for selection of feature, employment of MKSVM algorithm and stacking ensemble classifier for classification and application of the feature of fusion of different feature extraction methods.

Results: The algorithm under consideration has been put into practice using MATLAB, utilizing datasets from BRATS (Brain Tumor Segmentation) for the years 2013, 2015, and 2018. These datasets serve as the foundation for testing and validating the algorithm's performance across different time periods, providing a comprehensive assessment of its effectiveness in detecting brain tumors. The proposed algorithm achieves maximum detection accuracy, detection sensitivity and specificity up to 98%, 99% and 99.5% respectively. The experimental outcomes showcase the efficiency of the algorithm in detection of brain tumor.

Conclusion: The proposed work mainly contributes in brain tumor detection in the following aspects: a) use of combination of transform methods for texture feature extraction from MRI scans b) hybrid feature selection methods using firefly and glow-worm optimization algorithms for selection of feature c) employment of MKSVM algorithm and stacking ensemble classifier for classification and application of the feature of fusion of different feature extraction methods.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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