探讨室内/室外时间和氡暴露的差异可能是导致非吸烟妇女肺癌风险意外增加的因素。

Q3 Medicine
Arash Safari, Seyed Alireza Mortazavi, Abdolkarim Ghadimi-Moghadam, Masoud Haghani, Seyed Mohammad Javad Mortazavi, Lembit Sihver
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引用次数: 0

摘要

根据美国国立卫生研究院(NIH)的一项研究,与吸烟者相比,从未吸烟者中女性的肺癌发病率更高,发病年龄也更早。女性非吸烟者肺癌发病率的上升可能与吸入氡气有关,应对此进行进一步调查。我们的理论依据是男性和女性在氡暴露方面的差异,这可能是由于在室内和室外的时间不同造成的。在过去几年中,美国和其他发达国家的吸烟率持续下降。吸烟率的下降导致与肺癌相关的主要风险因素发生了新的变化。虽然烟草烟雾历来是导致肺癌的主要原因,但吸烟率的下降使得其他风险因素(如氡暴露)成为首要因素。鉴于某些国家的女性平均在室内度过的时间可能比男性更长,她们可能会接触到更高浓度的氡。氡暴露的增加可以解释女性非吸烟者肺癌发病率上升的原因。该理论仍处于初级阶段,需要进一步研究和验证。但是,如果被证明是正确的,它将极大地改变我们对肺癌风险因素的认识,并带来新的预防方法。因此,鉴于该理论对公共卫生的潜在影响,加快审查和公布该理论至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the Disparity in Indoor/Outdoor Time and Radon Exposure as Possible Factors Contributing to the Unexpected Increase in Lung Cancer Risk among Non-Smoking Women.

According to a NIH study, Lung cancer among individuals who have never smoked is more prevalent in women and occurs at an earlier age than in smokers. The rise in lung cancer rates among female non-smokers might be linked to radon inhalation and should be further investigated. Our theory is based on the differences in radon exposure between males and females, which can be attributed to the variations in time spent indoors versus outdoors. Over the past few years, the smoking rates have shown a steady decline in the United States and other developed countries. This decrease in smoking prevalence has led to a new shift in the primary risk factors associated with lung cancer. Although tobacco smoke historically served as the primary cause of lung cancer, the reduction in smoking rates has allowed other risk factors, such as radon exposure, to come to the forefront. Given that women in certain countries, on average, might spend more time indoors compared to men, they are potentially exposed to higher levels of radon. This increased exposure could explain the rising rates of lung cancer among female non-smokers. The theory is still in its nascent stages and requires further research and validation. However, if proven correct, it could significantly alter our understanding of lung cancer risk factors and lead to new prevention. It is therefore crucial to expedite the review and publication of this theory, given its potential implications for public health.

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来源期刊
Journal of Biomedical Physics and Engineering
Journal of Biomedical Physics and Engineering Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.90
自引率
0.00%
发文量
64
审稿时长
10 weeks
期刊介绍: The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.
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