先进混合闭环系统的卓越管理:波兰的经验教训。

IF 6.1 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Bartłomiej Matejko , Tim van den Heuvel , Javier Castaneda , Arcelia Arrieta , Katarzyna Cyranka , Ohad Cohen , Maciej Małecki , Tomasz Klupa
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引用次数: 0

摘要

研究背景本研究旨在分析波兰(PL)MiniMed 780G(MM780G)高级混合闭环(AHCL)系统用户的实际表现,并与除波兰以外的欧洲地区(EU-PL)进行比较,以找出造成潜在差异的因素。前者使用该技术在全球范围内取得了最佳范围内时间(TIR)结果:方法:分析 MM780G 系统用户在 2020 年 8 月至 2022 年 12 月期间上传的 CareLink 个人数据:结果:波兰用户(N=1304)的平均 TIR 为 79.1 ± 8.7 %(欧盟-波兰为 73.0 ± 10.0 %,N=55659),TBRC 结论:波兰 MM780G 用户的平均 TIR 为 79.1 ± 8.7 %(欧盟-波兰为 73.0 ± 10.0 %,N=55659):波兰 MM780G 用户的血糖控制情况优于欧洲一般人群(不包括波兰)。这在很大程度上归功于波兰采用了最佳设置,以及在系统启动时已经取得了较高的血糖结果。由于这些特点可以在其他地方实施,我们相信其他国家也能取得这一优异成绩。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Excellence in the management of Advanced Hybrid Closed-Loop Systems: Lessons from the Polish cohort

Background

The aim of the study was to analyze the real-world performance of MiniMed 780G (MM780G) Advanced Hybrid Closed Loop (AHCL) system users from Poland (PL) and compare it to the European region excluding Poland (EU-PL) in order to identify factors contributing to potential differences. The former achieved some of the best Time in Range (TIR) results globally using this technology.

Methods

CareLink Personal data uploaded by MM780G system users from August 2020 to December 2022 were analyzed.

Results

The Polish users (N=1304) on average reached to TIR of 79.1 ± 8.7 % (vs 73.0 ± 10.0 % for EU-PL, N=55659), a TBR<54 mg/dL of 0.6 ± 0.7 % (vs 0.4 ± 0.6 %) and a TBR<70 mg/dL of 2.9 ± 2.1 % (vs 2.1 ± 1.8 %). The adoption rate of optimal settings (i.e, GT=100 mg/dL, AIT=2hr) in PL was high (19.7 % vs 6.3 %), and filtering on optimal setting users led to less pronounced differences in glycemic control between PL and EU-PL. A univariable analysis with post-AHCL TIR showed that geography itself (PL vs EU-PL) is not a significant contributor to a high post-AHCL TIR (p = 0.15), and that much of the Polish post-AHCL TIR can be explained by the high pre-AHCL TIR.

Conclusion

The Polish MM780G users achieved better glycemic control than the general European population (excluding Poland). This is largely attributable to the adoption of optimal settings in Poland and the already high glycemic outcomes at system start. As these characteristics can be implemented elsewhere, we believe this outstanding result can be obtained in other countries as well.

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来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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