在光学相干断层扫描引导下对无保护的左主干远端分叉进行双吻合微型Culotte支架植入术:即时和短期疗效。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Saibal Mukhopadhyay MD, DM, Jamal Yusuf MD, DM, Ankit Bansal MD, DM, Rupesh Agrawal MD, DM, Vimal Mehta MD, DM, Mohit D. Gupta MD, DM, Girish M.P. MD, DM, Arima Nigam MD, DM, Safal Safal MD, DM, Vishal Batra MD, DM, Sanjeev Kathuria MD, DM, Ankur Gautam MD, DM, Subrat Kumar Muduli MD, DM, Sumod Kurian MD, DM
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引用次数: 0

摘要

导言Culotte 支架植入术是治疗左冠状动脉主干分叉病变的有效方法。Culotte支架术的主要缺点是侧支骨膜再狭窄增加。这是由于侧支骨膜处产生了餐巾环或潜在间隙。Toth 等人的一项工作台研究表明,在主血管支架植入术前进行额外的连续吻合球囊扩张可以防止这种畸形:在光学相干断层扫描(OCT)的指导下,我们中心在2020年3月至2022年12月期间对45名左主干远端(LM)疾病患者进行了DK迷你库洛特支架植入术:45例患者中[男性:35例(77.77%);平均年龄:63.67±4.94岁],26例(57.8%)存在慢性冠脉综合征,其余为不稳定型心绞痛。所有病变均为梅迪纳(1,1,1)、(0,1,1)或(1,0,1),中位句法评分为 28(IQR=23-29)。所有手术在技术上都很成功,没有发生不良临床事件(死亡、心肌梗死或支架血栓)。在 OCT 引导下,LM、左前降支(LAD)和左环挠(LCx)的最小支架面积(MSA)分别为 13.28 ± 0.77 mm2、8.25 ± 0.29 mm2 和 7.54 ± 0.45 mm2。所有病例的支架扩张率均大于 80%。一年后,主要心血管不良事件(MACE)发生率为 2.2%。此外,一名患者(2.2%)的侧支发生了再狭窄,但采取了保守治疗:结论:在左主干分叉远端进行DK微型库洛特支架植入术效果良好,能有效防止侧支支架变形及其支架内再狭窄的后遗症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Double Kissing Mini-Culotte Stenting in Unprotected Distal Left Main Bifurcation Under Optical Coherence Tomography Guidance: Immediate and Short-Term Outcomes

Culotte stenting is an effective strategy for left main coronary artery bifurcation lesions. Increased side branch ostial restenosis is the main drawback of culotte stenting. This is due to a napkin ring or potential gap produced at the ostium of the side branch. A bench study by Toth et al11 has shown that additional sequential kissing balloon dilation before main vessel stenting can prevent this deformity. We report immediate and short-term results of double kissing (DK) mini-culotte stenting with a 1-year angiographic follow-up.

Between March 2020 and December 2022, 45 patients with distal left main (LM) disease underwent DK mini-culotte stenting at our center under optical coherence tomography guidance. Of 45 patients (male: 35 (77.77%); mean age: 63.67 ± 4.94 years), chronic coronary artery syndrome was present in 26 (57.8%) and unstable angina in the remainder. All lesions were Medina (1,1,1), (0,1,1), or (1,0,1), with a median Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score of 28 (interquartile range 23 to 29). All procedures were technically successful with no adverse clinical events (death, myocardial infarction, or stent thrombosis). Under optical coherence tomography guidance, adequate minimal stent area of 13.28 ± 0.77 mm2, 8.25 ± 0.29 mm2, and 7.54 ± 0.45 mm2 was achieved in LM, left anterior descending, and left circumflex, respectively. Adequate stent expansion of >80% was achieved in all cases. At the end of 1 year, the incidence of major adverse cardiovascular events was 2.2%. Furthermore, restenosis of the side branch developed in 1 patient (2.2%), which was managed conservatively. DK mini-culotte stenting in the distal LM bifurcation has shown promising results and is effective in preventing side branch stent deformation and its sequelae of in-stent restenosis.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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