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OLAH 将脂肪酸代谢与呼吸道病毒性疾病的严重程度联系起来

IF 45.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Cell Pub Date : 2024-08-22 DOI:10.1016/j.cell.2024.07.032
Rohan Palanki, Hannah Yamagata, Michael J. Mitchell
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引用次数: 0

摘要

呼吸道病毒感染可能导致严重的呼吸道疾病，但人们对导致疾病严重程度的因素还不甚了解。在本期《细胞》杂志上，贾、克劳福德等人1 发现了油酰基-ACP-水解酶（OLAH）在介导与病毒性呼吸道疾病严重程度相关的危及生命的炎症中的作用。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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OLAH connects fatty acid metabolism to the severity of respiratory viral disease

Respiratory virus infections may cause profound respiratory illness, yet the factors that underlie disease severity are not well understood. In this issue of Cell, Jia, Crawford, et al.1 identify the role of oleoyl-ACP-hydrolase (OLAH) in mediating life-threatening inflammation associated with viral respiratory disease severity.

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来源期刊
Cell
Cell 生物-生化与分子生物学
CiteScore
110.00
自引率
0.80%
发文量
396
审稿时长
2 months
期刊介绍： Cells is an international, peer-reviewed, open access journal that focuses on cell biology, molecular biology, and biophysics. It is affiliated with several societies, including the Spanish Society for Biochemistry and Molecular Biology (SEBBM), Nordic Autophagy Society (NAS), Spanish Society of Hematology and Hemotherapy (SEHH), and Society for Regenerative Medicine (Russian Federation) (RPO). The journal publishes research findings of significant importance in various areas of experimental biology, such as cell biology, molecular biology, neuroscience, immunology, virology, microbiology, cancer, human genetics, systems biology, signaling, and disease mechanisms and therapeutics. The primary criterion for considering papers is whether the results contribute to significant conceptual advances or raise thought-provoking questions and hypotheses related to interesting and important biological inquiries. In addition to primary research articles presented in four formats, Cells also features review and opinion articles in its "leading edge" section, discussing recent research advancements and topics of interest to its wide readership.
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