{"title":"封底内页：角膜-SELEX：针对眼睛表面和脂质体药物递送的适配体（EXP2 4/2024）","authors":"Ka-Ying Wong, Yibo Liu, Man-Sau Wong, Juewen Liu","doi":"10.1002/EXP.20240403","DOIUrl":null,"url":null,"abstract":"<p>Via the tissue-SELEX method, a few cornea-targeting aptamers were isolated, facilitating the efficient delivery of cyclosporine A encapsulated in liposomes for both in vivo and in vitro management of dry eye disease. This approach ensures prolonged drug retention on the corneal surface, establishing a general platform for ocular drug delivery.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240403","citationCount":"0","resultStr":"{\"title\":\"Inside Back Cover: Cornea-SELEX for aptamers targeting the surface of eyes and liposomal drug delivery (EXP2 4/2024)\",\"authors\":\"Ka-Ying Wong, Yibo Liu, Man-Sau Wong, Juewen Liu\",\"doi\":\"10.1002/EXP.20240403\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Via the tissue-SELEX method, a few cornea-targeting aptamers were isolated, facilitating the efficient delivery of cyclosporine A encapsulated in liposomes for both in vivo and in vitro management of dry eye disease. This approach ensures prolonged drug retention on the corneal surface, establishing a general platform for ocular drug delivery.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":72997,\"journal\":{\"name\":\"Exploration (Beijing, China)\",\"volume\":\"4 4\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240403\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Exploration (Beijing, China)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240403\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Exploration (Beijing, China)","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240403","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inside Back Cover: Cornea-SELEX for aptamers targeting the surface of eyes and liposomal drug delivery (EXP2 4/2024)
Via the tissue-SELEX method, a few cornea-targeting aptamers were isolated, facilitating the efficient delivery of cyclosporine A encapsulated in liposomes for both in vivo and in vitro management of dry eye disease. This approach ensures prolonged drug retention on the corneal surface, establishing a general platform for ocular drug delivery.
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