大肠癌抑郁障碍的当前趋势和热点:一项文献计量学和视觉研究。

IF 2.5 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Zi-Wei Yan, Ying-Nan Liu, Qian Xu, Yuan Yuan
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引用次数: 0

摘要

背景:抑郁症与结直肠癌(CRC)密切相关。目的:通过对有关 CRC 与抑郁症关系的相关文献进行文献计量分析,确定研究现状和热点:方法:从 Web of Science Core Collection 收集有关 CRC 患者抑郁症的文章。使用CiteSpace和VOSviewer软件对文献计量网络进行可视化分析:从 2001 年到 2022 年,《癌症中的支持性治疗》、美国、蒂尔堡大学和 Mols 是最有影响力的期刊、国家、机构和作者姓名。关键词共现聚类分析将生活质量、焦虑和心理压力置于视觉网络图的中心。对相关作用机制研究的聚类进行了进一步的聚类分析,结果表明(1)细胞因子对 CRC 抑郁症的发生和发展起着至关重要的作用;(2)微RNA 对 CRC 抑郁症的发展起着至关重要的作用;(3)一些抗癌药物具有促抑郁活性;(4)选择性血清素再摄取抑制剂同时具有抗肿瘤和抗抑郁活性:结论:癌症患者的生活质量和心理护理是关键课题。细胞因子和 microRNA 的作用、抗癌药物的抑郁活性及其抗肿瘤特性值得深入研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current trends and hotspots of depressive disorders with colorectal cancer: A bibliometric and visual study.

Background: Depression is strongly associated with colorectal cancer (CRC). Few bibliometric analyses have systematically summarized the research focus and recent progress in this field.

Aim: To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between CRC and depression.

Methods: Articles on depression in CRC patients were collected from the Web of Science Core Collection. CiteSpace and VOSviewer software were used to visualize bibliometric networks.

Results: From 2001 to 2022, Supportive Care in Cancer, the United States, Tilburg University, and Mols were the most productive and influential journal, country, institution, and author name. Co-occurrence cluster analysis of keywords placed quality of life, anxiety, and psychological stress in the center of the visual network diagram. Further clustering was performed for the clusters with studies of the relevant mechanism of action, which showed that: (1) Cytokines have a role essential for the occurrence and development of depressive disorders in CRC; (2) MicroRNAs have a role essential for the development of depressive disorders in CRC; (3) Some anticancer drugs have pro-depressant activity; and (4) Selective serotonin reuptake inhibitors have both antitumor and antidepressant activity.

Conclusion: Life quality and psychological nursing of the cancer population were key topics. The roles of cytokines and microRNAs, the pro-depression activity of anticancer drugs and their antitumor properties deserve in-depth study.

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来源期刊
World Journal of Gastrointestinal Oncology
World Journal of Gastrointestinal Oncology Medicine-Gastroenterology
CiteScore
4.20
自引率
3.30%
发文量
1082
期刊介绍: The World Journal of Gastrointestinal Oncology (WJGO) is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of gastrointestinal oncology.
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