利用 LC-OCT 观察皮肤填充物在体内的位置。

IF 2 4区 医学 Q3 DERMATOLOGY
Noah Musolff, Bianca Sanabria, Victoria Caetano, Laura Pulgarin, Zaima Sohail Chaudhry, Babar Rao
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引用次数: 0

摘要

背景:皮肤填充剂已成为一种流行的非手术面部年轻化和改善方法。在美国,除肉毒素注射外,皮肤填充剂是最常见的非手术疗法。线场光学相干断层扫描(LC-OCT;deepLive 系统,法国达迈医疗公司)是无创皮肤成像技术的最新发展之一:我们对六名在面部不同位置接受透明质酸(HA)皮肤填充剂治疗的患者进行了 LC-OCT 图像采集。图像采集时间分别为填充前(T0)、填充后(T1)和 6 至 8 周后(T2)的随访:结果:在 T0 阶段,我们可以看到正常外观的表皮、真皮上皮交界处和真皮。在 T1 阶段,皮内填充物沉积显示为均匀的低反射区域,与周围的血管和其他结构清晰可辨。在 T2 时,沉积物可被分辨为低反射区域,但与 T1 时相比,沉积物的大小有所减小。在表面视图上,胶原纤维的厚度增加,组织更均匀,反射更强:我们证实了 LC-OCT 在无创评估皮肤 HA 填充物的短期和中期效果方面的实用性。LC-OCT 可能是评估填充物精确定位和跟踪所产生的体内变化的重要工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
LC-OCT as a tool to visualize in vivo location of dermal fillers.

Background: Dermal fillers have emerged as a popular non-surgical solution for facial rejuvenation and enhancement. Apart from botulinum toxin injections, they are the most common non-surgical procedure performed in the US. Line-field optical coherence tomography (LC-OCT; deepLive system Damae Medical, France) represents one of the most recent developments in non-invasive skin imaging technologies.

Materials and methods: We performed LC-OCT image acquisition on six patients that were treated with hyaluronic acid (HA) dermal fillers in various locations on the face. The images were acquired before the application of the fillers (T0), immediately after (T1), and at a 6- to 8-week (T2) follow-up visit.

Results: At T0, we were able to appreciate a normal-appearing epidermis, dermoepithelial junction, and dermis. At T1, the intradermal filler deposits appeared as homogeneously hyporeflective areas, clearly discernible from surrounding vessels and other structures. At T2, the deposits were distinguishable as hyporeflective areas, although they were diminished in size compared to T1. On enface view, collagen fibers had increased thickness and were more homogeneously organized and hyperreflective.

Conclusions: We established the usefulness of LC-OCT in the non-invasive evaluation of dermal HA fillers to visualize both short-term and medium-term effects. LC-OCT may be a valuable tool in evaluating the precise location of filler placement and follow-up of resulting in vivo changes.

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来源期刊
Skin Research and Technology
Skin Research and Technology 医学-皮肤病学
CiteScore
3.30
自引率
9.10%
发文量
95
审稿时长
6-12 weeks
期刊介绍: Skin Research and Technology is a clinically-oriented journal on biophysical methods and imaging techniques and how they are used in dermatology, cosmetology and plastic surgery for noninvasive quantification of skin structure and functions. Papers are invited on the development and validation of methods and their application in the characterization of diseased, abnormal and normal skin. Topics include blood flow, colorimetry, thermography, evaporimetry, epidermal humidity, desquamation, profilometry, skin mechanics, epiluminiscence microscopy, high-frequency ultrasonography, confocal microscopy, digital imaging, image analysis and computerized evaluation and magnetic resonance. Noninvasive biochemical methods (such as lipids, keratin and tissue water) and the instrumental evaluation of cytological and histological samples are also covered. The journal has a wide scope and aims to link scientists, clinical researchers and technicians through original articles, communications, editorials and commentaries, letters, reviews, announcements and news. Contributions should be clear, experimentally sound and novel.
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