根据具有全国代表性的横断面 H-UNCOVER 研究,匈牙利确诊和未确诊糖尿病的患病率和决定因素。

IF 6.1 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
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引用次数: 0

摘要

目的:估算匈牙利已确诊糖尿病(dDM)和未确诊糖尿病(uDM)的患病率,并调查uDM的决定因素:数据来自具有全国代表性的 H-UNCOVER 研究。由于匈牙利 11/19 个县都有实验室测量数据,因此符合条件的人数为 5974/17787 人。dDM 由自我报告定义,而 uDM 是指自我报告为阴性且空腹血糖升高(≥7 mmol/l)和/或 HbA1c 升高(≥48 mmol/mol)。在对年龄和体重指数进行调整后,使用复合样本的逻辑回归计算出 dDM 和 uDM 的比较结果:糖尿病患病率为 12.0%/11.9%(女性/男性,95%CI:10.7-13.4%/10.7-13.2%),而 2.2%/2.8%(1.7-2.8%/2.2-3.6%)的女性/男性为 uDM。虽然uDM与dDM的比例在≥40岁的女性中相似,但40多岁的男性患uDM的几率最高。失业率(女性/男性OR:0.58 [0.14-2.45]/0.50 [0.13-1.92])和教育水平(大专与小学;女性/男性OR:1.16 [0.53-2.56]/ 0.53 [0.24-1.18])均与uDM无关。患有慢性疾病的男女患尿毒症的风险都较低:我们报告的糖尿病和未确诊糖尿病患病率高于匈牙利以前的估计值。社会经济因素与uDM无关的发现表明,全民医疗保健可以提供公平的糖尿病诊断机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prevalence and determinants of diagnosed and undiagnosed diabetes in Hungary based on the nationally representative cross-sectional H-UNCOVER study

Prevalence and determinants of diagnosed and undiagnosed diabetes in Hungary based on the nationally representative cross-sectional H-UNCOVER study

Aims

To estimate prevalence of diagnosed (dDM) and undiagnosed diabetes (uDM) in Hungary and investigate determinants of uDM.

Methods

Data was obtained from the nationally representative H-UNCOVER study. As laboratory measurements were available for 11/19 Hungarian counties, n = 5,974/17,787 people were eligible. After exclusions, 5,673 (representing 4,976,097 people) were included. dDM was defined by self-reporting, while uDM as negative self-reporting and elevated fasting glucose (≥7 mmol/l) and/or HbA1c (≥48 mmol/mol). Logistic regression for complex samples was used to calculate comparisons between dDM and uDM adjusted for age and BMI.

Results

Diabetes prevalence was 12.0 %/11.9 % (women/men, 95 %CI:10.7–13.4 %/10.7–13.2 %), while 2.2 %/2.8 % (1.7–2.8 %/2.2–3.6 %) of women/men were uDM. While the proportion of uDM vs. dDM was similar for women ≥ 40, men in their forties had the highest odds for uDM. Neither unemployment (women/men OR:0.58 [0.14–2.45]/0.50 [0.13–1.92]), nor education level (tertiary vs. primary; women/men OR: 1.16 [0.53–2.56]/ 0.53 [0.24–1.18]) were associated with uDM. The risk of uDM was lower in both sexes with chronic morbidities.

Conclusions

We report higher prevalence of diabetes and undiagnosed diabetes than previous Hungarian estimates. The finding that socioeconomic factors are not associated to uDM suggests that universal health care could provide equitable access to diabetes diagnosis.

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来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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