氯菌灵对辣椒疫病的双重作用：破坏疫霉菌丝和激活 CaCNGC9 介导的 SA 信号转导

IF 3.8 1区农林科学 Q1 AGRONOMY

Pest Management Science Pub Date : 2024-08-21 DOI:10.1002/ps.8383

Xin Zhu, Aihong Zou, Rui Liao, Jianjian Zhang, Changyun Liu, Chuanxiang Wang, Chunyan Hao, Daoquan Cheng, Lunfei Chen, Xianchao Sun

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引用次数: 0

摘要

辣椒疫病是由疫霉（Phytophthora capsici）引起的一种毁灭性病害，严重威胁着全世界的辣椒生产。随着辣椒疫霉菌对传统杀菌剂产生抗药性，迫切需要探索新的替代品来防治辣椒疫霉菌病。本研究旨在评估一种由色氨酸合成的化合物--氯阴康唑（CHI）对辣椒疫病的抑制作用，并探索其潜在的作用机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dual actions of chloroinconazide on pepper blight in Capsicum annuum: disruption of Phytophthora capsici mycelium and activation of CaCNGC9-mediated SA signaling

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Dual actions of chloroinconazide on pepper blight in Capsicum annuum: disruption of Phytophthora capsici mycelium and activation of CaCNGC9-mediated SA signaling

BACKGROUND

Pepper blight, caused by Phytophthora capsici, is a devastating disease that seriously threatens pepper production worldwide. With the emergence of resistance in P. capsici against conventional fungicides, there is an urgent need to explore novel alternatives for pepper blight management. This study aims to assess the inhibitory effect of chloroinconazide (CHI), a compound synthesized from tryptophan, against pepper blight, and to explore its potential mechanisms of action.

RESULTS

The results demonstrated that CHI effectively targeted P. capsici, disrupting its growth and mycelial structure, which resulted in the release of dissolved intracellular substances. Additionally, CHI significantly inhibited the sporangium formation, zoospores release, and zoospores germination, thereby reducing the re-infection of P. capsici. In contrast, the commercial pesticide methylaxyl only inhibited mycelial growth and had limited effect on re-infection, while azoxystrobin inhibited re-infection but had a weak inhibitory effect on mycelial growth. Furthermore, CHI activated the salicylic acid (SA) signaling pathway-mediated immune response to inhibit P. capsici infection in pepper, with this activation being contingent upon cyclic nucleotide-gated ion channel CaCNGC9.

CONCLUSION

CHI exhibited potent dual inhibitory effects on P. capsici by disrupting mycelial structure and activating the CaCNGC9-mediated SA signaling pathway. These dual mechanisms of action suggested that CHI could serve as a promising alternative chemical fungicide for the effective management of pepper blight, offering a new approach to control this devastating disease. Our findings highlighted the potential of CHI as a sustainable and efficient solution to combat the increasing resistance of P. capsici to conventional fungicides, ensuring better crop protection and yield. © 2024 Society of Chemical Industry.

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来源期刊

Pest Management Science 农林科学-昆虫学

CiteScore

7.90

自引率

9.80%

发文量

553

审稿时长

4.8 months

期刊介绍： Pest Management Science is the international journal of research and development in crop protection and pest control. Since its launch in 1970, the journal has become the premier forum for papers on the discovery, application, and impact on the environment of products and strategies designed for pest management. Published for SCI by John Wiley & Sons Ltd.