{"title":"微补丁激活的中性粒细胞在肿瘤免疫疗法中大有可为","authors":"Mengran Chen, Bingyang Chu, Yu Wu","doi":"10.1002/mba2.93","DOIUrl":null,"url":null,"abstract":"<p>This study used polymer micropatches as a platform for sustained and targeted activation of neutrophils. The micropatches can promote the rapid conversion of neutrophils to the N1 type while also enhancing the activation of other immune cells in vivo. The activated neutrophils are recruited to the tumor site, where they exert effective antitumor effects.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":100901,"journal":{"name":"MedComm – Biomaterials and Applications","volume":"3 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mba2.93","citationCount":"0","resultStr":"{\"title\":\"Neutrophils activated by micropatches hold promising prospects in tumor immunotherapy\",\"authors\":\"Mengran Chen, Bingyang Chu, Yu Wu\",\"doi\":\"10.1002/mba2.93\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This study used polymer micropatches as a platform for sustained and targeted activation of neutrophils. The micropatches can promote the rapid conversion of neutrophils to the N1 type while also enhancing the activation of other immune cells in vivo. The activated neutrophils are recruited to the tumor site, where they exert effective antitumor effects.\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":100901,\"journal\":{\"name\":\"MedComm – Biomaterials and Applications\",\"volume\":\"3 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mba2.93\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MedComm – Biomaterials and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/mba2.93\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MedComm – Biomaterials and Applications","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/mba2.93","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neutrophils activated by micropatches hold promising prospects in tumor immunotherapy
This study used polymer micropatches as a platform for sustained and targeted activation of neutrophils. The micropatches can promote the rapid conversion of neutrophils to the N1 type while also enhancing the activation of other immune cells in vivo. The activated neutrophils are recruited to the tumor site, where they exert effective antitumor effects.
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