潜在创伤事件对原有焦虑和抑郁症状恢复的影响以及创伤后应激障碍的风险。

IF 5 3区 医学 Q1 CLINICAL NEUROLOGY
Psychiatry and Clinical Neurosciences Pub Date : 2024-11-01 Epub Date: 2024-08-20 DOI:10.1111/pcn.13725
Peter G van der Velden, Carlo Contino, Lonneke Lenferink, Marcel Das, Lutz Wittmann
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引用次数: 0

摘要

目的:最近发生的潜在创伤事件(PTEs)在多大程度上阻碍了原有心理健康问题的恢复,这在很大程度上还是个未知数。同样,未从先前存在的心理健康问题中恢复过来也会增加创伤后应激障碍(PTSD)的风险。本研究旨在深入了解这些影响:数据来自荷兰现代社会受害者(VICTIMS)研究的六次年度人口调查。在参与随后两次调查(标注为 T1 和 T2,n = 6942)的成年受访者中,选取了在 T1 时有严重焦虑和抑郁症状(ADS)的受访者(n = 487)。我们区分了 T1 和 T2 期间接触过 PTE 的受访者(PTE 组,n = 162)和未接触过 PTE 的受访者(对比组,n = 325)。我们采用了五项康复指标(基于可靠变化指数 (RCI)、症状减轻程度和 T2 临界分数)。我们使用多变量逻辑回归法研究了 T2 期 ADS 和可能的创伤后应激障碍恢复情况的差异:结果:在控制 11 个不同变量的情况下(0.40 ≤ 调整 OR ≤ 0.66),根据所有五个康复指标,PTE 组在 T1 和 T2 期间从严重 ADS 中康复的频率低于对比组。未康复的创伤后应激障碍组患者在T2时患可能创伤后应激障碍的比例(63%-82%)远高于康复者(0%-29%;8.96 ≤ 调整OR ≤ 26.33):结论:近期发生的潜在创伤事件会阻碍原有焦虑和抑郁症状的恢复,从而增加可能患创伤后应激障碍的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effects of potentially traumatic events on the recovery from pre-existing anxiety and depression symptomatology and the risk of PTSD.

Aim: The extent to which recent potentially traumatic events (PTEs) hinder the recovery from pre-existing mental health problems is largely unknown. The same applies to the extent to which non-recovery from pre-existing mental health problems increases the risk of posttraumatic stress disorder (PTSD). The aim of the present study is to gain insight in these effects.

Methods: Data were extracted from six annual surveys of the Dutch population-based Victims in Modern Society (VICTIMS) study. Of the adult respondents who participated in two subsequent surveys (labeled T1 and T2, n = 6942), those with severe anxiety and depression symptoms (ADS) at T1 (n = 487) were selected. We distinguished respondents exposed to PTEs (PTE-group, n = 162) and not exposed to PTEs (comparison group, n = 325) between T1 and T2. We applied five indicators of recovery [based on the Reliable Change Index (RCI), degrees of symptom reduction, and the cut-off score at T2]. Differences in the recovery from ADS and probable PTSD at T2 were examined using multivariate logistic regression.

Results: The PTE group less often recovered from severe ADS between T1 and T2 than the comparison group according to all five indicators of recovery, while controlling for 11 different variables (0.40 ≤ adjusted OR's ≤ 0.66). Those in the PTE group who did not recover, considerably more often suffered from probable PTSD at T2 (63%-82%) than those who did recover (0%-29%; 8.96 ≤ adjusted OR ≤ 26.33).

Conclusion: Recent potentially traumatic events hinder the recovery from pre-existing anxiety and depression symptomatology and thereby increase the risk of probable PTSD.

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来源期刊
CiteScore
7.40
自引率
4.20%
发文量
181
审稿时长
6-12 weeks
期刊介绍: PCN (Psychiatry and Clinical Neurosciences) Publication Frequency: Published 12 online issues a year by JSPN Content Categories: Review Articles Regular Articles Letters to the Editor Peer Review Process: All manuscripts undergo peer review by anonymous reviewers, an Editorial Board Member, and the Editor Publication Criteria: Manuscripts are accepted based on quality, originality, and significance to the readership Authors must confirm that the manuscript has not been published or submitted elsewhere and has been approved by each author
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