{"title":"Leber congenital amaurosis 研究的出版趋势：2002-2022 年期间的文献计量学研究。","authors":"Xiao-Xu Huang, Yi-Min Wang, Min-Yue Xie, Yi-Qing Sun, Xiao-Huan Zhao, Yu-Hong Chen, Jie-Qiong Chen, Si-Yang Han, Min-Wen Zhou, Xiao-Dong Sun","doi":"10.18240/ijo.2024.08.17","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To analyze the changes in scientific output relating to Leber congenital amaurosis (LCA) and forecast the study trends in this field.</p><p><strong>Methods: </strong>All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science (WOS) database. We analyzed the quantity (number of publications), quality (citation and H-index) and development trends (relative research interest, RRI) of published LCA research over the last two decades. Moreover, VOSviewer software was applied to define the co-occurrence network of keywords in this field.</p><p><strong>Results: </strong>A total of 2158 publications were ultimately examined. We found that the focus on LCA kept rising and peaked in 2015 and 2018, which is consistent with the development trend of gene therapy. The USA has contributed most to this field with 1162 publications, 56 674 citations and the highest H-index value (116). The keywords analysis was divided into five clusters to show the hotspots in the field of LCA, namely mechanism-related, genotype-related, local phenotype-related, system phenotype-related, and therapy-related. We also identified gene therapy and anti-retinal degeneration therapy as a major focus in recent years.</p><p><strong>Conclusion: </strong>Our study illustrates historical research process and future development trends in LCA field. 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引用次数: 0
摘要
目的：分析与Leber先天性无脑症（LCA）相关的科研成果的变化，并预测该领域的研究趋势：从 Web of Science (WOS) 数据库中收集了 2002 年至 2022 年间在 LCA 领域发表的所有论文。我们分析了近二十年来发表的生命周期评估研究的数量（论文数量）、质量（引用和 H 指数）和发展趋势（相对研究兴趣，RRI）。此外，还使用 VOSviewer 软件定义了该领域关键词的共现网络：结果：最终共研究了 2158 篇出版物。我们发现，对LCA的关注度持续上升，并在2015年和2018年达到顶峰，这与基因治疗的发展趋势一致。美国在这一领域的贡献最大，共发表论文 1162 篇，被引 56 674 次，H 指数值最高（116）。通过关键词分析，我们将LCA领域的热点分为五组，即机制相关、基因型相关、局部表型相关、系统表型相关和治疗相关。我们还发现基因治疗和抗视网膜变性治疗是近年来的研究重点：我们的研究说明了 LCA 领域的历史研究进程和未来发展趋势。结论：我们的研究说明了 LCA 领域的历史研究过程和未来发展趋势，这可能有助于指导进一步的临床诊断、治疗和科学研究。
Publication trends of Leber congenital amaurosis researches: a bibliometric study during 2002-2022.
Aim: To analyze the changes in scientific output relating to Leber congenital amaurosis (LCA) and forecast the study trends in this field.
Methods: All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science (WOS) database. We analyzed the quantity (number of publications), quality (citation and H-index) and development trends (relative research interest, RRI) of published LCA research over the last two decades. Moreover, VOSviewer software was applied to define the co-occurrence network of keywords in this field.
Results: A total of 2158 publications were ultimately examined. We found that the focus on LCA kept rising and peaked in 2015 and 2018, which is consistent with the development trend of gene therapy. The USA has contributed most to this field with 1162 publications, 56 674 citations and the highest H-index value (116). The keywords analysis was divided into five clusters to show the hotspots in the field of LCA, namely mechanism-related, genotype-related, local phenotype-related, system phenotype-related, and therapy-related. We also identified gene therapy and anti-retinal degeneration therapy as a major focus in recent years.
Conclusion: Our study illustrates historical research process and future development trends in LCA field. This may help to guide the orientation for further clinical diagnosis, treatment and scientific research.
期刊介绍：
· International Journal of Ophthalmology-IJO (English edition) is a global ophthalmological scientific publication
and a peer-reviewed open access periodical (ISSN 2222-3959 print, ISSN 2227-4898 online).
This journal is sponsored by Chinese Medical Association Xi’an Branch and obtains guidance and support from
WHO and ICO (International Council of Ophthalmology). It has been indexed in SCIE, PubMed,
PubMed-Central, Chemical Abstracts, Scopus, EMBASE , and DOAJ. IJO JCR IF in 2017 is 1.166.
IJO was established in 2008, with editorial office in Xi’an, China. It is a monthly publication. General Scientific
Advisors include Prof. Hugh Taylor (President of ICO); Prof.Bruce Spivey (Immediate Past President of ICO);
Prof.Mark Tso (Ex-Vice President of ICO) and Prof.Daiming Fan (Academician and Vice President,
Chinese Academy of Engineering.
International Scientific Advisors include Prof. Serge Resnikoff (WHO Senior Speciatist for Prevention of
blindness), Prof. Chi-Chao Chan (National Eye Institute, USA) and Prof. Richard L Abbott (Ex-President of
AAO/PAAO) et al.
Honorary Editors-in-Chief: Prof. Li-Xin Xie(Academician of Chinese Academy of
Engineering/Honorary President of Chinese Ophthalmological Society); Prof. Dennis Lam (President of APAO) and
Prof. Xiao-Xin Li (Ex-President of Chinese Ophthalmological Society).
Chief Editor: Prof. Xiu-Wen Hu (President of IJO Press).
Editors-in-Chief: Prof. Yan-Nian Hui (Ex-Director, Eye Institute of Chinese PLA) and
Prof. George Chiou (Founding chief editor of Journal of Ocular Pharmacology & Therapeutics).
Associate Editors-in-Chief include:
Prof. Ning-Li Wang (President Elect of APAO);
Prof. Ke Yao (President of Chinese Ophthalmological Society) ;
Prof.William Smiddy (Bascom Palmer Eye instituteUSA) ;
Prof.Joel Schuman (President of Association of University Professors of Ophthalmology,USA);
Prof.Yizhi Liu (Vice President of Chinese Ophtlalmology Society);
Prof.Yu-Sheng Wang (Director of Eye Institute of Chinese PLA);
Prof.Ling-Yun Cheng (Director of Ocular Pharmacology, Shiley Eye Center, USA).
IJO accepts contributions in English from all over the world. It includes mainly original articles and review articles,
both basic and clinical papers.
Instruction is Welcome Contribution is Welcome Citation is Welcome
Cooperation organization
International Council of Ophthalmology(ICO), PubMed, PMC, American Academy of Ophthalmology, Asia-Pacific, Thomson Reuters, The Charlesworth Group, Crossref,Scopus,Publons, DOAJ etc.
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