Filipe Vilas-Boas, Giacomo Emanuele Maria Rizzo, Charles De Ponthaud, Stuart Robinson, Sebastien Gaujoux, Gabriele Capurso, Giuseppe Vanella, Bahadır Bozkırlı
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引用次数: 0
摘要
恶性胃出口梗阻（mGOO）是影响胰腺周围肿瘤（包括胰腺癌）患者的主要疾病。目前的治疗方法包括外科胃肠造口术、内镜下支架植入术以及最近的 EUS 引导下胃肠造口术。大多数比较这三种手术效果的研究都侧重于技术成功率、临床成功率和安全性。一些与患者观点和视角相关的 "隐性 "结果可能会最终影响癌症相关和整体生存，如体质量组成、营养生物标志物、化疗耐受性和患者报告的生活质量。本综述旨在概述在未来围绕 mGOO 治疗方案的比较研究中应探索的潜在关键结果。
Unveiling hidden outcomes in malignant gastric outlet obstruction research - insights from a "Pancreas 2000" review.
Malignant gastric outlet obstruction (mGOO) is a major condition affecting patients with periampullary tumors, including pancreatic cancer. The current treatment options include surgical gastroenterostomy, endoscopic stenting and more recently EUS-guided gastroenterostomy. Most studies comparing the outcomes of the three procedures focus on technical success, clinical success and safety. Several "occult" outcomes relevant to the patient's viewpoints and perspective may ultimately impact on cancer-related and overall survival, such as body mass composition, nutritional biomarkers, chemotherapy tolerance and patient-reported quality of life. The aim of this review is to provide an overview of potential key outcomes that should be explored in future comparative research around mGOO treatment options.
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