Rebekka Søgaard, Pia Brunn Poulsen, Rikke Munch Gelardi, Susann Geschke, Jakob Ferløv Baselius Schwensen, Jeanne Duus Johansen
{"title":"化妆品中隐藏的甲醛","authors":"Rebekka Søgaard, Pia Brunn Poulsen, Rikke Munch Gelardi, Susann Geschke, Jakob Ferløv Baselius Schwensen, Jeanne Duus Johansen","doi":"10.1111/cod.14669","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Formaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without formaldehyde releasers, has previously been detected in cosmetic products.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>The objective of this study was to investigate the content and causes of hidden formaldehyde in leave-on cosmetic products.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>The formaldehyde release from 142 cosmetic products, primarily creams, was analysed using the chromotropic acid (CA) method. The study included 130 products with no formaldehyde releasers on the ingredient list and 12 products with formaldehyde releasers. Products without formaldehyde releasers positive to CA, that is, with formaldehyde ≥2.5 ppm, were additionally analysed using high-performance liquid chromatography (HPLC). Formaldehyde release from selected raw materials and packaging were also investigated.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Hidden formaldehyde was found in 23 of the 130 products (18%) without formaldehyde releasers on the ingredient list. The average formaldehyde content was 105 ppm (range: 0.5–507 ppm) in products with hidden formaldehyde and 355 ppm (range: 75–637 ppm) in eight products with formaldehyde releasers, selected for HPLC analysis. Impurities of formaldehyde in dihydroxyacetone may be a cause of hidden formaldehyde in self-tanners. No clear pattern was found for the other products with hidden formaldehyde.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Changes in regulation are needed to prevent allergic contact dermatitis from hidden formaldehyde in cosmetic products.</p>\n </section>\n </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"91 6","pages":"497-502"},"PeriodicalIF":4.8000,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.14669","citationCount":"0","resultStr":"{\"title\":\"Hidden formaldehyde in cosmetic products\",\"authors\":\"Rebekka Søgaard, Pia Brunn Poulsen, Rikke Munch Gelardi, Susann Geschke, Jakob Ferløv Baselius Schwensen, Jeanne Duus Johansen\",\"doi\":\"10.1111/cod.14669\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Formaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without formaldehyde releasers, has previously been detected in cosmetic products.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>The objective of this study was to investigate the content and causes of hidden formaldehyde in leave-on cosmetic products.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>The formaldehyde release from 142 cosmetic products, primarily creams, was analysed using the chromotropic acid (CA) method. The study included 130 products with no formaldehyde releasers on the ingredient list and 12 products with formaldehyde releasers. Products without formaldehyde releasers positive to CA, that is, with formaldehyde ≥2.5 ppm, were additionally analysed using high-performance liquid chromatography (HPLC). Formaldehyde release from selected raw materials and packaging were also investigated.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Hidden formaldehyde was found in 23 of the 130 products (18%) without formaldehyde releasers on the ingredient list. The average formaldehyde content was 105 ppm (range: 0.5–507 ppm) in products with hidden formaldehyde and 355 ppm (range: 75–637 ppm) in eight products with formaldehyde releasers, selected for HPLC analysis. Impurities of formaldehyde in dihydroxyacetone may be a cause of hidden formaldehyde in self-tanners. No clear pattern was found for the other products with hidden formaldehyde.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Changes in regulation are needed to prevent allergic contact dermatitis from hidden formaldehyde in cosmetic products.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10527,\"journal\":{\"name\":\"Contact Dermatitis\",\"volume\":\"91 6\",\"pages\":\"497-502\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.14669\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Contact Dermatitis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cod.14669\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contact Dermatitis","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cod.14669","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ALLERGY","Score":null,"Total":0}
Formaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without formaldehyde releasers, has previously been detected in cosmetic products.
Objectives
The objective of this study was to investigate the content and causes of hidden formaldehyde in leave-on cosmetic products.
Methods
The formaldehyde release from 142 cosmetic products, primarily creams, was analysed using the chromotropic acid (CA) method. The study included 130 products with no formaldehyde releasers on the ingredient list and 12 products with formaldehyde releasers. Products without formaldehyde releasers positive to CA, that is, with formaldehyde ≥2.5 ppm, were additionally analysed using high-performance liquid chromatography (HPLC). Formaldehyde release from selected raw materials and packaging were also investigated.
Results
Hidden formaldehyde was found in 23 of the 130 products (18%) without formaldehyde releasers on the ingredient list. The average formaldehyde content was 105 ppm (range: 0.5–507 ppm) in products with hidden formaldehyde and 355 ppm (range: 75–637 ppm) in eight products with formaldehyde releasers, selected for HPLC analysis. Impurities of formaldehyde in dihydroxyacetone may be a cause of hidden formaldehyde in self-tanners. No clear pattern was found for the other products with hidden formaldehyde.
Conclusions
Changes in regulation are needed to prevent allergic contact dermatitis from hidden formaldehyde in cosmetic products.
期刊介绍：
Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
