{"title":"疑似与胃腺癌有关的抗利尿激素分泌失调的副肿瘤综合征。","authors":"A Thomas, J Finlay, C Sharp","doi":"10.1111/avj.13365","DOIUrl":null,"url":null,"abstract":"<p>This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5-year-old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"102 10","pages":"510-513"},"PeriodicalIF":1.3000,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog\",\"authors\":\"A Thomas, J Finlay, C Sharp\",\"doi\":\"10.1111/avj.13365\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5-year-old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.</p>\",\"PeriodicalId\":8661,\"journal\":{\"name\":\"Australian Veterinary Journal\",\"volume\":\"102 10\",\"pages\":\"510-513\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian Veterinary Journal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/avj.13365\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Veterinary Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/avj.13365","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
本报告描述了一例疑似抗利尿激素不当副肿瘤综合征(SIADH)的病例,病犬是一只 5 岁的雄性澳大利亚海带犬,患有胃腺癌。该犬有慢性呕吐史,并伴有低钠血症、低钾血症、低氯血症和尿钠增加。计算机断层扫描确定了胃肿瘤的存在,组织病理学证实是幽门胃腺癌。通过比尔罗斯 I 型手术切除肿瘤后,电解质紊乱很快得到缓解。该犬术后六个月仍然存活,在发表文章时,SIADH 和肿瘤均未复发。
Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog
This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5-year-old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.
期刊介绍:
Over the past 80 years, the Australian Veterinary Journal (AVJ) has been providing the veterinary profession with leading edge clinical and scientific research, case reports, reviews. news and timely coverage of industry issues. AJV is Australia''s premier veterinary science text and is distributed monthly to over 5,500 Australian Veterinary Association members and subscribers.