Isabelle D. de Oliveira , Eduardo Ferreira-Machado , Jamile M. Garcia , Sarah R.J.S. Simões , Ketlyn B. Figueiredo , Rodrigo A. Ressio , André L.M. da Costa , Flora N. Matos , Cássia R.R. Gonzaga , Shamira S. Leandro , Marina A. de Medeiros , Rodrigo H.F. Teixeira , Mariana C. Martins , Juliana P.F. Takahashi , Leonardo J.T. de Araújo , Natália C.C. de Azevedo Fernandes , Juliana M. Guerra
{"title":"一只人工饲养的西部黑手犭(Saguinus niger)体内的散播性副球孢子菌病","authors":"Isabelle D. de Oliveira , Eduardo Ferreira-Machado , Jamile M. Garcia , Sarah R.J.S. Simões , Ketlyn B. Figueiredo , Rodrigo A. Ressio , André L.M. da Costa , Flora N. Matos , Cássia R.R. Gonzaga , Shamira S. Leandro , Marina A. de Medeiros , Rodrigo H.F. Teixeira , Mariana C. Martins , Juliana P.F. Takahashi , Leonardo J.T. de Araújo , Natália C.C. de Azevedo Fernandes , Juliana M. Guerra","doi":"10.1016/j.jcpa.2024.07.005","DOIUrl":null,"url":null,"abstract":"<div><p>Paracoccidioidomycosis (PCM) is an endemic fungal disease that occurs in Latin America and primarily affects humans. The disease has been rarely documented in non-human primates. This report details a disseminated and fatal case of PCM caused by <em>Paracoccidioides brasiliensis</em> in a western black-handed tamarin (<em>Saguinus niger</em>) under human care. Histopathological examination revealed extensive pyogranulomatous inflammation in the lungs, spleen, liver, lymph nodes, kidneys, epididymis, right testicle, heart, adrenal gland and intestines, associated with characteristic yeast forms consistent with <em>Paracoccidioides</em> spp and confirmed by immunohistochemistry. Molecular analysis indicated a high nucleotide similarity with <em>P. brasiliensis</em> sequences for both the <em>18S</em> rRNA and <em>gp43</em> genes. This naturally occurring infection highlights the susceptibility of these animals to PCM and their role in ecoepidemiology warrants further investigation.</p></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"214 ","pages":"Pages 1-6"},"PeriodicalIF":0.8000,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Disseminated paracoccidioidomycosis in a captive western black-handed tamarin (Saguinus niger)\",\"authors\":\"Isabelle D. de Oliveira , Eduardo Ferreira-Machado , Jamile M. Garcia , Sarah R.J.S. Simões , Ketlyn B. Figueiredo , Rodrigo A. Ressio , André L.M. da Costa , Flora N. Matos , Cássia R.R. Gonzaga , Shamira S. Leandro , Marina A. de Medeiros , Rodrigo H.F. Teixeira , Mariana C. Martins , Juliana P.F. Takahashi , Leonardo J.T. de Araújo , Natália C.C. de Azevedo Fernandes , Juliana M. Guerra\",\"doi\":\"10.1016/j.jcpa.2024.07.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Paracoccidioidomycosis (PCM) is an endemic fungal disease that occurs in Latin America and primarily affects humans. The disease has been rarely documented in non-human primates. This report details a disseminated and fatal case of PCM caused by <em>Paracoccidioides brasiliensis</em> in a western black-handed tamarin (<em>Saguinus niger</em>) under human care. Histopathological examination revealed extensive pyogranulomatous inflammation in the lungs, spleen, liver, lymph nodes, kidneys, epididymis, right testicle, heart, adrenal gland and intestines, associated with characteristic yeast forms consistent with <em>Paracoccidioides</em> spp and confirmed by immunohistochemistry. Molecular analysis indicated a high nucleotide similarity with <em>P. brasiliensis</em> sequences for both the <em>18S</em> rRNA and <em>gp43</em> genes. This naturally occurring infection highlights the susceptibility of these animals to PCM and their role in ecoepidemiology warrants further investigation.</p></div>\",\"PeriodicalId\":15520,\"journal\":{\"name\":\"Journal of Comparative Pathology\",\"volume\":\"214 \",\"pages\":\"Pages 1-6\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-08-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Comparative Pathology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0021997524002858\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PATHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Comparative Pathology","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021997524002858","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PATHOLOGY","Score":null,"Total":0}
Disseminated paracoccidioidomycosis in a captive western black-handed tamarin (Saguinus niger)
Paracoccidioidomycosis (PCM) is an endemic fungal disease that occurs in Latin America and primarily affects humans. The disease has been rarely documented in non-human primates. This report details a disseminated and fatal case of PCM caused by Paracoccidioides brasiliensis in a western black-handed tamarin (Saguinus niger) under human care. Histopathological examination revealed extensive pyogranulomatous inflammation in the lungs, spleen, liver, lymph nodes, kidneys, epididymis, right testicle, heart, adrenal gland and intestines, associated with characteristic yeast forms consistent with Paracoccidioides spp and confirmed by immunohistochemistry. Molecular analysis indicated a high nucleotide similarity with P. brasiliensis sequences for both the 18S rRNA and gp43 genes. This naturally occurring infection highlights the susceptibility of these animals to PCM and their role in ecoepidemiology warrants further investigation.
期刊介绍：
The Journal of Comparative Pathology is an International, English language, peer-reviewed journal which publishes full length articles, short papers and review articles of high scientific quality on all aspects of the pathology of the diseases of domesticated and other vertebrate animals.
Articles on human diseases are also included if they present features of special interest when viewed against the general background of vertebrate pathology.
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