基于欧米茄脂肪酸的疗法可帮助患有复杂并发症的患者愈合顽固伤口。

IF 1.7 4区 医学 Q3 DERMATOLOGY
Advances in Skin & Wound Care Pub Date : 2024-10-01 Epub Date: 2024-08-16 DOI:10.1097/ASW.0000000000000207
Jacob Reinkraut, Adeen Khokhar, Sarah Abdou, Sonya Wali, Desmond Bell
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引用次数: 0

摘要

摘要:人体具有在受伤后通过复杂、连续的阶段进行自我修复的独特能力。目前开发的先进伤口护理疗法通常侧重于解决这一生物过程中的一个方面,这可能导致伤口愈合延迟或无效。在本病例报告中,作者展示了使用新型多模式伤口基质治疗如何加快两名患者的伤口愈合并减轻疼痛,这两名患者均在使用先进疗法超过 7 个月后仍无反应。第一位患者患有因子 V 莱顿,第二位患者患有镰状细胞病。采用每周一次的多模式伤口基质治疗方案,并在临床需要时结合锐性清创术,可消除疼痛,加快伤口愈合直至闭合。伤口基质的欧米茄脂肪酸配方是针对难以愈合的伤口中常见的多种因素设计的,这些因素如果得不到解决,就会对伤口愈合级联产生不利的抑制作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Omega Fatty Acid-Based Therapy for Healing of Recalcitrant Wounds in Patients with Complex Comorbidities.

Abstract: The human body possesses the unique ability to repair itself after injury through complex, sequential phases. Current development of advanced wound care therapies generally focuses on addressing a single aspect of this biological process that can result in delayed or ineffective wound healing. When patients present with further systemic and local confounding pathologies, it can result in painful, chronic wounds that are especially challenging to treat.In this case report, the authors demonstrate how treatment with a novel multimodal wound matrix expedited healing and decreased pain in two patients who had each been unresponsive to treatment with advanced modalities for more than 7 months. The first patient had factor V Leiden, and the second patient had sickle cell disease. Use of a once-weekly treatment protocol with the multimodal wound matrix, combined with sharp debridement when deemed clinically necessary, resulted in elimination of pain and expedited wound healing to closure. The wound matrix's omega fatty acid-based formulation is designed to target multiple factors common among hard-to-heal wounds that when not addressed can adversely inhibit the wound-healing cascade.

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来源期刊
Advances in Skin & Wound Care
Advances in Skin & Wound Care DERMATOLOGY-NURSING
CiteScore
2.50
自引率
12.50%
发文量
271
审稿时长
>12 weeks
期刊介绍: A peer-reviewed, multidisciplinary journal, Advances in Skin & Wound Care is highly regarded for its unique balance of cutting-edge original research and practical clinical management articles on wounds and other problems of skin integrity. Each issue features CME/CE for physicians and nurses, the first journal in the field to regularly offer continuing education for both disciplines.
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