氰化物中毒中的亚甲蓝:一名继发性小脑梗塞患者的病例报告。

Johanna Catherine Ruiz Castillo , Sara Margarita Benedetti Ramírez , Miguel Antonio Tolosa Rodríguez
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引用次数: 0

摘要

氰化物中毒的死亡率非常高,因为这种化学物质会对人体产生破坏性影响,迅速损害人体的重要功能。尽管亚甲蓝长期以来一直被认为是对抗氰化物中毒影响的一种选择,但几十年来对其作用机制和有效性的研究一直很有限,对其保护作用和特性的研究也是如此。本文介绍了一例急性氰化钾中毒患者的临床病例,该患者对亚甲蓝的解毒治疗反应良好;然而,尽管她没有明显的临床表现,却因中毒引发了小脑中风。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Azul de metileno en intoxicación por cianuro: reporte de caso en paciente con infarto cerebeloso secundario

Mortality rates from cyanide poisoning are significantly high due to the devastating effects that this chemical substance can trigger in the body, quickly compromising vital functions. Currently, within the treatment strategies, circulatory and ventilatory support stands out, along with the administration of specific antidotes, which are difficult to access and are not usually available in most hospitals.

Although methylene blue has long been considered an option to counteract the effects of cyanide poisoning, research on its mechanisms of action and effectiveness has been limited for decades, leaving aside its protective effects and properties. unique redox in mitochondrial complexes and the Krebs cycle. A clinical case is presented of a patient with acute potassium cyanide poisoning who responded to antidotal treatment with methylene blue; However, she developed a cerebellar stroke as a consequence of the poisoning, despite having no apparent clinical manifestations.

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