防治非洲锥虫病抗药性的 "一个健康 "政策

IF 4.1 2区 医学 Q1 INFECTIOUS DISEASES
Keneth Iceland Kasozi , Ewan Thomas MacLeod , Susan Christina Welburn
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引用次数: 0

摘要

非洲锥虫抗药性(ATr)的增加受到多种因素的影响,如病原体的进化变化、人群中存在抗药性基因、决策失误、公私合作伙伴关系对当地社区的参与有限,以及过去六十年来用于开发新药的资金不足。20 世纪中叶药物自由化政策执行不力,导致中低收入国家(LMICs)兽药药物警戒工作不力,从而加剧了这些挑战。疾病管理框架 "同一健康"(OH)在管理 2004 年禽流感和最近的 COVID-19 大流行等流行病方面取得了成功,并迅速建立了机构合作关系,它为应对兽药残留提供了切实可行的解决方案。为应对反兽疫,由国际和当地合作伙伴在政策和基层层面共同参与的 "吴倡议 "对于激发社区兴趣至关重要。政治承诺、媒体参与和非政府组织的重要性无论怎样强调都不为过,因为它们对低收入和中等收入国家的资源调动和长期可持续性至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
One Health policy for combatting African trypanocide resistance

The rise of African trypanocide resistance (ATr) is influenced by various factors such as evolutionary changes in the pathogen, the presence of resistance genes in the population, poor policy decisions, limited private-public partnerships to engage local communities, and insufficient funding for the development of new drugs over the past sixty years. These challenges have been exacerbated by the inadequate implementation of drug liberalization policies in the mid 20th century, leading to poor pharmacovigilance practices for veterinary drugs in low and middle income countries (LMICs). One health (OH), a disease management framework, provides practical solutions for addressing ATr, drawing on its success in managing previous epidemics like avian influenza in 2004 and the recent COVID-19 pandemic, where institutional collaborations were rapidly established. To combat ATr, OH initiatives involving both international and local partners at the policy and grassroots levels are crucial to generate community interest. The importance of political commitment, media involvement, and nongovernmental organizations cannot be overstated, as they are essential for resource mobilization and long-term sustainability in LMICs.

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来源期刊
One Health
One Health Medicine-Infectious Diseases
CiteScore
8.10
自引率
4.00%
发文量
95
审稿时长
18 weeks
期刊介绍: One Health - a Gold Open Access journal. The mission of One Health is to provide a platform for rapid communication of high quality scientific knowledge on inter- and intra-species pathogen transmission, bringing together leading experts in virology, bacteriology, parasitology, mycology, vectors and vector-borne diseases, tropical health, veterinary sciences, pathology, immunology, food safety, mathematical modelling, epidemiology, public health research and emergency preparedness. As a Gold Open Access journal, a fee is payable on acceptance of the paper. Please see the Guide for Authors for more information. Submissions to the following categories are welcome: Virology, Bacteriology, Parasitology, Mycology, Vectors and vector-borne diseases, Co-infections and co-morbidities, Disease spatial surveillance, Modelling, Tropical Health, Discovery, Ecosystem Health, Public Health.
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