治疗白色念珠菌感染的纳米机器人

IF 11 1区综合性期刊 Q1 Multidisciplinary

Research Pub Date : 2024-08-15 eCollection Date: 2024-01-01 DOI:10.34133/research.0455

Yanling Hu, Guisheng Zeng, Yue Wang, Dongliang Yang

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引用次数: 0

摘要

白色念珠菌是人类的一种机会性真菌病原体。它可引起各种感染，从浅表的皮肤黏膜疾病到严重的全身性疾病，导致大量的发病和死亡。这种病原体经常形成生物膜，对抗真菌药物和宿主免疫系统产生抗药性，导致治疗失败。最近的研究表明，纳米机器人具有穿透生物屏障和破坏真菌生物膜的潜力。在这篇视角论文中，我们简要概述了纳米机器人在治疗念珠菌病方面的最新突破，并讨论了当前的挑战和前景。

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Nanorobots to Treat Candida albicans Infection.

Candida albicans is an opportunistic fungal pathogen of humans. It causes a variety of infections ranging from superficial mucocutaneous conditions to severe systemic diseases that result in substantial morbidity and mortality. This pathogen frequently forms biofilms resistant to antifungal drugs and the host immune system, leading to treatment failures. Recent research has demonstrated the potential of nanorobots to penetrate biological barriers and disrupt fungal biofilms. In this perspective paper, we provide a brief overview of recent breakthroughs in nanorobots for candidiasis treatment and discuss current challenges and prospects.

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来源期刊

Research Multidisciplinary-Multidisciplinary

CiteScore

13.40

自引率

3.60%

发文量

审稿时长

14 weeks

期刊介绍： Research serves as a global platform for academic exchange, collaboration, and technological advancements. This journal welcomes high-quality research contributions from any domain, with open arms to authors from around the globe. Comprising fundamental research in the life and physical sciences, Research also highlights significant findings and issues in engineering and applied science. The journal proudly features original research articles, reviews, perspectives, and editorials, fostering a diverse and dynamic scholarly environment.