对从萨斯喀彻温省血液透析患者身上分离出的隧道式血液透析导管进行微生物分析。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2024-09-01 Epub Date: 2024-08-16 DOI:10.1080/17460913.2024.2359879
Murugesan Sivaranjani, Haley Sanderson, Chinenye R Nnajide, Anna Martens-Koop, Joseph M Blondeau, Rodrick Stryker, Aaron P White
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引用次数: 0

摘要

目的:比较有症状和无症状患者血液透析导管内的微生物群落,以确定它们之间的差异:萨斯喀彻温省卫生局在 18 个月内从患者身上拔出导管(n = 41)。对导管在体内的部分进行冲洗,并使用依赖培养和不依赖培养的分析方法对导管内容物进行评估:结果:所有导管都有细菌定植,根据微生物群落和检测到的单个物种,各组之间有相当大的重叠。通过测序检测到的革兰氏阴性菌种较多,而培养出的主要是革兰氏阳性菌株。抗生素耐药性和生物膜的形成很普遍,但与导管组别无关:结论:每组导管中都能检测到常见的病原体,因此很难根据微生物学来预测感染情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microbiological analysis of tunneled hemodialysis catheters isolated from patients receiving hemodialysis in Saskatchewan.

Aim: To compare the microbial communities inside hemodialysis catheters from symptomatic and asymptomatic patients to determine their differences.Materials & methods: Catheters (n = 41) were removed from patients in the Saskatchewan Health Authority over an 18-month period. The catheter section inside the body was flushed and the contents were evaluated using culture-dependent and culture-independent analysis.Results: All catheters were colonized by bacteria, with considerable overlap between groups based on microbial communities and the individual species detected. More Gram-negative species were detected by sequencing, whereas predominantly Gram-positive strains were cultured. Antibiotic resistance and biofilm formation was widespread and not correlated with either catheter group.Conclusion: Common pathogens were detected in each set of catheters, therefore predicting infections based on the microbiology is difficult.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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