新型经皮层 PRK 与传统酒精辅助 PRK 的比较:角膜密度测量和比色法研究。

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
Jaime Aramberri, Gorka Lauzirika, Igor Illarramendi, Javier Mendicute
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引用次数: 0

摘要

目的:描述并比较使用酒精辅助光屈光性角膜切除术(aaPRK)或单步经上皮角膜屈光手术(tPRK)进行角膜屈光手术后的角膜密度测量、主观屈光度、视力和角膜高阶像差(HOA):我们进行了一项回顾性观察研究。我们分析了 120 名连续接受 aaPRK 或 tPRK 矫正 6 度以内近视和 2 度以内散光的健康近视患者的 120 只右眼。所有病例均使用 WaveLight EX500 准分子激光(Alcon Laboratories, Inc.)在术前检查和 6 个月随访时进行了视力、主观屈光度和 Pentacam AXL® 测量。Pentacam AXL® 软件用于评估不同角膜深度和角膜前部 HOA(分析区域为 6 毫米)的不同环形角膜光密度:各组术前球面等值相似(aaPRK 组和 tPRK 组分别为 -3.07 ± 1.52 和 -3.38 ± 1.46)。各组之间的视力和术后屈光度没有明显的统计学差异。术后角膜密度测定在任何研究区域均未显示出统计学意义上的显著差异,两种手术方法的结果相似。然而,HOA分析显示,两种技术之间存在显著的统计学差异(aaPRK组和tPRK组分别为1.42 ± 0.39和1.80 ± 0.62;P = 0.000):结论:aaPRK 和单步 tPRK 的视觉、屈光和角膜密度效果相当。结论:aaPRK 和单步 tPRK 的视力、屈光度和角膜密度结果相当,HOA 存在一些差异,但与临床无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison between a new transepithelial PRK vs. conventional alcohol-assisted PRK: Corneal densitometry and aberrometry study.

Purpose: To describe and compare corneal densitometry, subjective refraction, visual acuity, and corneal higher order aberrations (HOA) after corneal refractive surgery using either alcohol-assisted photorefractive keratectomy (aaPRK) or single-step transepithelial PRK (tPRK).

Methods: We conducted a retrospective and observational study. We analyzed 120 right eyes from 120 healthy consecutive myopic patients who underwent aaPRK or tPRK to correct myopia of up to 6 diopters and astigmatism of up to 2 diopters. The WaveLight EX500 excimer laser (Alcon Laboratories, Inc.) was used in all cases. Visual acuity, subjective refraction, and Pentacam AXL® measurements were performed at the preoperative visit and at 6-months follow-up visit. Pentacam AXL® software was used to assess corneal optical density in various annuli for different corneal depths and anterior corneal HOA (6 mm area of analysis).

Results: Preoperative spherical equivalent values were similar between groups preoperatively (-3.07 ± 1.52 and -3.38 ± 1.46 in the aaPRK and tPRK groups, respectively). There were no statistically significant differences in visual acuity and postoperative refraction between groups. Postoperative corneal densitometry did not show statistically significant differences in any of the areas studied and both surgical procedures obtained similar results. However, analysis of HOA showed statistically significant differences between the techniques (1.42 ± 0.39 and 1.80 ± 0.62 for the aaPRK and tPRK groups, respectively; p = 0.000).

Conclusions: Both aaPRK and single-step tPRK gave comparable visual, refractive, and corneal density outcomes. Some differences were observed in HOA but were not clinically relevant.

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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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