Amirhossein Sheida, Marjan Farshadi, Amirhossein Mirzaei, Shakiba Najjar Khalilabad, Fatemeh Zarepour, Seyed Pouya Taghavi, Maryam Sadat Hosseini Khabr, Fatemeh Ravaei, Sara Rafiei, Kimia Mosadeghi, Mohammad Sepehr Yazdani, Ali Fakhraie, Alireza Ghattan, Mohammad Masoud Zamani Fard, Maryam Shahyan, Moein Rafiei, Neda Rahimian, Sayyed Alireza Talaei Zavareh, Hamed Mirzaei
{"title":"天然产品治疗胶质瘤的潜力：关注分子机制。","authors":"Amirhossein Sheida, Marjan Farshadi, Amirhossein Mirzaei, Shakiba Najjar Khalilabad, Fatemeh Zarepour, Seyed Pouya Taghavi, Maryam Sadat Hosseini Khabr, Fatemeh Ravaei, Sara Rafiei, Kimia Mosadeghi, Mohammad Sepehr Yazdani, Ali Fakhraie, Alireza Ghattan, Mohammad Masoud Zamani Fard, Maryam Shahyan, Moein Rafiei, Neda Rahimian, Sayyed Alireza Talaei Zavareh, Hamed Mirzaei","doi":"10.1007/s12013-024-01447-x","DOIUrl":null,"url":null,"abstract":"<div><p>Despite the waning of traditional treatments for glioma due to possible long-term issues, the healing possibilities of substances derived from nature have been reignited in the scientific community. These natural substances, commonly found in fruits and vegetables, are considered potential alternatives to pharmaceuticals, as they have been shown in prior research to impact pathways surrounding cancer progression, metastases, invasion, and resistance. This review will explore the supposed molecular mechanisms of different natural components, such as berberine, curcumin, coffee, resveratrol, epigallocatechin-3-gallate, quercetin, tanshinone, silymarin, coumarin, and lycopene, concerning glioma treatment. While the benefits of a balanced diet containing these compounds are widely recognized, there is considerable scope for investigating the efficacy of these natural products in treating glioma.</p></div>","PeriodicalId":510,"journal":{"name":"Cell Biochemistry and Biophysics","volume":"82 4","pages":"3157 - 3208"},"PeriodicalIF":2.5000,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Potential of Natural Products in the Treatment of Glioma: Focus on Molecular Mechanisms\",\"authors\":\"Amirhossein Sheida, Marjan Farshadi, Amirhossein Mirzaei, Shakiba Najjar Khalilabad, Fatemeh Zarepour, Seyed Pouya Taghavi, Maryam Sadat Hosseini Khabr, Fatemeh Ravaei, Sara Rafiei, Kimia Mosadeghi, Mohammad Sepehr Yazdani, Ali Fakhraie, Alireza Ghattan, Mohammad Masoud Zamani Fard, Maryam Shahyan, Moein Rafiei, Neda Rahimian, Sayyed Alireza Talaei Zavareh, Hamed Mirzaei\",\"doi\":\"10.1007/s12013-024-01447-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Despite the waning of traditional treatments for glioma due to possible long-term issues, the healing possibilities of substances derived from nature have been reignited in the scientific community. These natural substances, commonly found in fruits and vegetables, are considered potential alternatives to pharmaceuticals, as they have been shown in prior research to impact pathways surrounding cancer progression, metastases, invasion, and resistance. This review will explore the supposed molecular mechanisms of different natural components, such as berberine, curcumin, coffee, resveratrol, epigallocatechin-3-gallate, quercetin, tanshinone, silymarin, coumarin, and lycopene, concerning glioma treatment. While the benefits of a balanced diet containing these compounds are widely recognized, there is considerable scope for investigating the efficacy of these natural products in treating glioma.</p></div>\",\"PeriodicalId\":510,\"journal\":{\"name\":\"Cell Biochemistry and Biophysics\",\"volume\":\"82 4\",\"pages\":\"3157 - 3208\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-08-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Biochemistry and Biophysics\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12013-024-01447-x\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Biochemistry and Biophysics","FirstCategoryId":"99","ListUrlMain":"https://link.springer.com/article/10.1007/s12013-024-01447-x","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Potential of Natural Products in the Treatment of Glioma: Focus on Molecular Mechanisms
Despite the waning of traditional treatments for glioma due to possible long-term issues, the healing possibilities of substances derived from nature have been reignited in the scientific community. These natural substances, commonly found in fruits and vegetables, are considered potential alternatives to pharmaceuticals, as they have been shown in prior research to impact pathways surrounding cancer progression, metastases, invasion, and resistance. This review will explore the supposed molecular mechanisms of different natural components, such as berberine, curcumin, coffee, resveratrol, epigallocatechin-3-gallate, quercetin, tanshinone, silymarin, coumarin, and lycopene, concerning glioma treatment. While the benefits of a balanced diet containing these compounds are widely recognized, there is considerable scope for investigating the efficacy of these natural products in treating glioma.
期刊介绍：
Cell Biochemistry and Biophysics (CBB) aims to publish papers on the nature of the biochemical and biophysical mechanisms underlying the structure, control and function of cellular systems
The reports should be within the framework of modern biochemistry and chemistry, biophysics and cell physiology, physics and engineering, molecular and structural biology. The relationship between molecular structure and function under investigation is emphasized.
Examples of subject areas that CBB publishes are:
· biochemical and biophysical aspects of cell structure and function;
· interactions of cells and their molecular/macromolecular constituents;
· innovative developments in genetic and biomolecular engineering;
· computer-based analysis of tissues, cells, cell networks, organelles, and molecular/macromolecular assemblies;
· photometric, spectroscopic, microscopic, mechanical, and electrical methodologies/techniques in analytical cytology, cytometry and innovative instrument design
For articles that focus on computational aspects, authors should be clear about which docking and molecular dynamics algorithms or software packages are being used as well as details on the system parameterization, simulations conditions etc. In addition, docking calculations (virtual screening, QSAR, etc.) should be validated either by experimental studies or one or more reliable theoretical cross-validation methods.
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