Gianmarco D Bigotto, Antonio Podo Brunetti, Stefania Guida, Giorgio Stabile, Nathalie Rizzo, Franco Rongioletti
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引用次数: 0
摘要
摘要：原发性皮肤纺锤形B细胞淋巴瘤是一种不常见的皮肤淋巴瘤亚型，其特点是肿瘤性B细胞呈明显的纺锤形细胞学。尽管在临床、组织病理学和表型上与原发性皮肤滤泡中心淋巴瘤（B细胞淋巴瘤的一种惰性形式）相似，但它也表现出与原发性皮肤弥漫大B细胞淋巴瘤相似的某些特征。值得注意的是，在极少数情况下，患者的临床病程更具侵袭性。本报告详细介绍了一例罕见的原发性皮肤纺锤形细胞 B 细胞滤泡中心淋巴瘤，表现为长期单发的卡他性脱发斑。此外，我们还对文献中记载的现有病例进行了全面回顾。
Primary Cutaneous Spindle Cell B-Cell Follicle Center Lymphoma Presenting as Long-Standing Plaque of Cicatricial Alopecia: A Case Report With a Comprehensive Review of the Literature.
Abstract: Primary cutaneous spindle B-cell lymphoma is an uncommon subtype of cutaneous lymphoma characterized by a distinct spindled cytology of neoplastic B cells. Despite sharing clinical, histopathological, and phenotypical similarities with primary cutaneous follicle center lymphoma, an indolent form of B-cell lymphoma, it also exhibits certain features akin to primary cutaneous diffuse large B-cell lymphoma. Notably, in rare instances, a more aggressive clinical course has been observed. This report details a rare case of primary cutaneous spindle cell B-cell follicle center lymphoma, manifested as a prolonged solitary plaque of cicatricial alopecia. In addition, we provide a comprehensive review of existing cases documented in the literature.
期刊介绍：
The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports.
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