时间定格：成熟囊性畸胎瘤恶变的术中诊断和处理。

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Journal of Mid-life Health Pub Date : 2024-04-01 Epub Date: 2024-07-05 DOI:10.4103/jmh.jmh_253_23

Arun Sudhakar Sanap, Medha D Davile, Anusha A Kamath, Shuchita R Mundle

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引用次数: 0

摘要

卵巢恶性转化（MCT）是影响老年人的罕见并发症，其中最常见的是鳞状细胞癌。其预后会随着卵巢外扩散而恶化。我们报告了两例 MCT 衍生的 SCC。患者表现为腹部肿块、疼痛、肠道症状，有时伴有体重减轻；造影显示为 MCT。年龄（51-60 岁）、绝经后状态、体积大（>20 厘米）、双侧、卵巢病变复杂，这些都引起了对恶性肿瘤的怀疑。其中一个病例的肿瘤标志物（如癌抗原-125 和乳酸脱氢酶）升高。术中冰冻切片证实了恶性肿瘤，为分期开腹手术提供了指导。有一例病例经组织病理学检查为晚期。术中冰冻切片有助于最佳分期。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Frozen in Time: Intraoperative Diagnosis and Management of Malignant Transformation in Mature Cystic Teratoma.

Malignant transformation (MCT) of ovary is rare complications affecting elderly, squamous cell carcinoma being the most common. The prognosis worsens with extraovarian spread. We present two cases of MCT-derived SCC. Patients exhibited abdominal lump, pain, bowel symptoms, sometimes with weight loss; imaging revealed MCT. Age (51-60), postmenopausal status, large size (>20 cm), bilaterality, and complex ovarian lesions raised suspicion of malignancy. Elevated tumor markers (e.g., cancer antigen-125 and lactate dehydrogenase) were noted in one case. Intraoperative frozen section confirmed malignancy, guiding staging laparotomy. One case was advanced stage on histopathology. Intraoperative frozen section aids optimal staging.

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来源期刊

Journal of Mid-life Health Social Sciences-Health (social science)

CiteScore

1.70

自引率

9.10%

发文量

审稿时长

43 weeks

期刊介绍： Journal of mid-life health is the official journal of the Indian Menopause society published Quarterly in January, April, July and October. It is peer reviewed, scientific journal of mid-life health and its problems. It includes all aspects of mid-life health, preventive as well as curative. The journal publishes on subjects such as gynecology, neurology, geriatrics, psychiatry, endocrinology, urology, andrology, psychology, healthy ageing, cardiovascular health, bone health, quality of life etc. as relevant of men and women in their midlife. The Journal provides a visible platform to the researchers as well as clinicians to publish their experiences in this area thereby helping in the promotion of mid-life health leading to healthy ageing, growing need due to increasing life expectancy. The Editorial team has maintained high standards and published original research papers, case reports and review articles from the best of the best contributors both national & international, consistently so that now, it has become a great tool in the hands of menopause practitioners.