{"title":"用于双模可穿戴式心脏监护仪的多功能多孔软复合材料","authors":"Zehua Chen, Sicheng Chen, Syed Muntazir Andrabi, Ganggang Zhao, Yadong Xu, Qunle Ouyang, Milton E. Busquets, Xiaoyan Qian, Sandeep Gautam, Pai-Yen Chen, Jingwei Xie, Zheng Yan","doi":"10.1002/aic.18576","DOIUrl":null,"url":null,"abstract":"Wearable heart monitors are crucial for early diagnosis and treatment of heart diseases in non-clinical settings. However, their long-term applications require skin-interfaced materials that are ultrasoft, breathable, antibacterial, and possess robust, enduring on-skin adherence—features that remain elusive. Here, we have developed multifunctional porous soft composites that meet all these criteria for skin-interfaced bimodal cardiac monitoring. The composite consists of a bilayer structure featuring phase-separated porous elastomer and slot-die-coated biogel. The porous elastomer ensures ultrasoftness, breathability, ease of handling, and mechanical integrity, while the biogel enables long-term on-skin adherence. Additionally, we incorporated ε-polylysine in the biogel to offer antibacterial properties. Also, the conductive biogel embedded with silver nanowires was developed for use in electrocardiogram sensors to reduce contact impedance and ensure high-fidelity recordings. Furthermore, we assembled a bimodal wearable cardiac monitoring system that demonstrates high-fidelity recordings of both cardiac electrical (electrocardiogram) and mechanical (seismocardiogram) signals over a 14-day testing period.","PeriodicalId":120,"journal":{"name":"AIChE Journal","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Multifunctional porous soft composites for bimodal wearable cardiac monitors\",\"authors\":\"Zehua Chen, Sicheng Chen, Syed Muntazir Andrabi, Ganggang Zhao, Yadong Xu, Qunle Ouyang, Milton E. Busquets, Xiaoyan Qian, Sandeep Gautam, Pai-Yen Chen, Jingwei Xie, Zheng Yan\",\"doi\":\"10.1002/aic.18576\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Wearable heart monitors are crucial for early diagnosis and treatment of heart diseases in non-clinical settings. However, their long-term applications require skin-interfaced materials that are ultrasoft, breathable, antibacterial, and possess robust, enduring on-skin adherence—features that remain elusive. Here, we have developed multifunctional porous soft composites that meet all these criteria for skin-interfaced bimodal cardiac monitoring. The composite consists of a bilayer structure featuring phase-separated porous elastomer and slot-die-coated biogel. The porous elastomer ensures ultrasoftness, breathability, ease of handling, and mechanical integrity, while the biogel enables long-term on-skin adherence. Additionally, we incorporated ε-polylysine in the biogel to offer antibacterial properties. Also, the conductive biogel embedded with silver nanowires was developed for use in electrocardiogram sensors to reduce contact impedance and ensure high-fidelity recordings. Furthermore, we assembled a bimodal wearable cardiac monitoring system that demonstrates high-fidelity recordings of both cardiac electrical (electrocardiogram) and mechanical (seismocardiogram) signals over a 14-day testing period.\",\"PeriodicalId\":120,\"journal\":{\"name\":\"AIChE Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-08-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"AIChE Journal\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1002/aic.18576\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, CHEMICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"AIChE Journal","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/aic.18576","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, CHEMICAL","Score":null,"Total":0}
Multifunctional porous soft composites for bimodal wearable cardiac monitors
Wearable heart monitors are crucial for early diagnosis and treatment of heart diseases in non-clinical settings. However, their long-term applications require skin-interfaced materials that are ultrasoft, breathable, antibacterial, and possess robust, enduring on-skin adherence—features that remain elusive. Here, we have developed multifunctional porous soft composites that meet all these criteria for skin-interfaced bimodal cardiac monitoring. The composite consists of a bilayer structure featuring phase-separated porous elastomer and slot-die-coated biogel. The porous elastomer ensures ultrasoftness, breathability, ease of handling, and mechanical integrity, while the biogel enables long-term on-skin adherence. Additionally, we incorporated ε-polylysine in the biogel to offer antibacterial properties. Also, the conductive biogel embedded with silver nanowires was developed for use in electrocardiogram sensors to reduce contact impedance and ensure high-fidelity recordings. Furthermore, we assembled a bimodal wearable cardiac monitoring system that demonstrates high-fidelity recordings of both cardiac electrical (electrocardiogram) and mechanical (seismocardiogram) signals over a 14-day testing period.
期刊介绍:
The AIChE Journal is the premier research monthly in chemical engineering and related fields. This peer-reviewed and broad-based journal reports on the most important and latest technological advances in core areas of chemical engineering as well as in other relevant engineering disciplines. To keep abreast with the progressive outlook of the profession, the Journal has been expanding the scope of its editorial contents to include such fast developing areas as biotechnology, electrochemical engineering, and environmental engineering.
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Soft Materials: Synthesis, Processing and Products
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