Irene Císcar García , Isabel de la Fuente Muñoz , Pilar Sánchez Henarejos , Pedro Marín Rodríguez , Caridad Marín Hernández , Carmen María Servet Pérez de Lema , Jose Luis Alonso Romero , Antonio Piñero Madrona
{"title":"乳房切除术后重建及其与浸润性乳腺癌辅助放疗的关系：一个悬而未决的问题？","authors":"Irene Císcar García , Isabel de la Fuente Muñoz , Pilar Sánchez Henarejos , Pedro Marín Rodríguez , Caridad Marín Hernández , Carmen María Servet Pérez de Lema , Jose Luis Alonso Romero , Antonio Piñero Madrona","doi":"10.1016/j.senol.2024.100617","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Post-mastectomy radiotherapy is vital in the treatment of breast cancer because it improves survival. Post-mastectomy breast reconstruction impacts quality of life, but adjuvant radiotherapy is controversial, due to the complications it entails. This study examines the relationship between radiotherapy and the complications in reconstruction, with consideration of the moment in time and the technique employed.</p></div><div><h3>Methods</h3><p>A single-centre, retrospective study was conducted with 273 patients treated with mastectomy and reconstruction. Radiotherapy was assessed as an independent variable in relation to its complications. Demographic, anatomopathological, surgical and treatment variables were analysed.</p></div><div><h3>Results</h3><p>The general rate of complications was 42.2%, with fat necrosis and capsular contracture being the most common. There was no significant relationship between radiotherapy and complications in general, but there was a trend towards more complications with immediate reconstructions. Autologous reconstruction was associated with fewer complications than heterologous, particularly with radiotherapy.</p></div><div><h3>Discussion</h3><p>Although previous studies suggest there is an association between radiotherapy and morbidity in post-mastectomy reconstruction, this study did not find any direct connection. The importance of distinguishing between complications at the donor and recipient sites stood out. Immediate reconstruction demonstrated a larger number of complications with radiotherapy, supporting the recommendation to postpone it. Autologous reconstruction was highlighted as the preferred option.</p></div><div><h3>Conclusions</h3><p>The study did not find a direct association between radiotherapy in post-mastectomy reconstruction patients and complications in general. However, it revealed a correlation between complications and heterologous techniques, emphasising the preference for autologous reconstructions.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 4","pages":"Article 100617"},"PeriodicalIF":0.2000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"La reconstrucción posmastectomía y su relación con la radioterapia adyuvante en el tratamiento del cáncer invasivo de mama: ¿asunto cerrado?\",\"authors\":\"Irene Císcar García , Isabel de la Fuente Muñoz , Pilar Sánchez Henarejos , Pedro Marín Rodríguez , Caridad Marín Hernández , Carmen María Servet Pérez de Lema , Jose Luis Alonso Romero , Antonio Piñero Madrona\",\"doi\":\"10.1016/j.senol.2024.100617\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Post-mastectomy radiotherapy is vital in the treatment of breast cancer because it improves survival. Post-mastectomy breast reconstruction impacts quality of life, but adjuvant radiotherapy is controversial, due to the complications it entails. This study examines the relationship between radiotherapy and the complications in reconstruction, with consideration of the moment in time and the technique employed.</p></div><div><h3>Methods</h3><p>A single-centre, retrospective study was conducted with 273 patients treated with mastectomy and reconstruction. Radiotherapy was assessed as an independent variable in relation to its complications. Demographic, anatomopathological, surgical and treatment variables were analysed.</p></div><div><h3>Results</h3><p>The general rate of complications was 42.2%, with fat necrosis and capsular contracture being the most common. There was no significant relationship between radiotherapy and complications in general, but there was a trend towards more complications with immediate reconstructions. Autologous reconstruction was associated with fewer complications than heterologous, particularly with radiotherapy.</p></div><div><h3>Discussion</h3><p>Although previous studies suggest there is an association between radiotherapy and morbidity in post-mastectomy reconstruction, this study did not find any direct connection. The importance of distinguishing between complications at the donor and recipient sites stood out. Immediate reconstruction demonstrated a larger number of complications with radiotherapy, supporting the recommendation to postpone it. Autologous reconstruction was highlighted as the preferred option.</p></div><div><h3>Conclusions</h3><p>The study did not find a direct association between radiotherapy in post-mastectomy reconstruction patients and complications in general. However, it revealed a correlation between complications and heterologous techniques, emphasising the preference for autologous reconstructions.</p></div>\",\"PeriodicalId\":38058,\"journal\":{\"name\":\"Revista de Senologia y Patologia Mamaria\",\"volume\":\"37 4\",\"pages\":\"Article 100617\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2024-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista de Senologia y Patologia Mamaria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0214158224000458\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Senologia y Patologia Mamaria","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0214158224000458","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
La reconstrucción posmastectomía y su relación con la radioterapia adyuvante en el tratamiento del cáncer invasivo de mama: ¿asunto cerrado?
Introduction
Post-mastectomy radiotherapy is vital in the treatment of breast cancer because it improves survival. Post-mastectomy breast reconstruction impacts quality of life, but adjuvant radiotherapy is controversial, due to the complications it entails. This study examines the relationship between radiotherapy and the complications in reconstruction, with consideration of the moment in time and the technique employed.
Methods
A single-centre, retrospective study was conducted with 273 patients treated with mastectomy and reconstruction. Radiotherapy was assessed as an independent variable in relation to its complications. Demographic, anatomopathological, surgical and treatment variables were analysed.
Results
The general rate of complications was 42.2%, with fat necrosis and capsular contracture being the most common. There was no significant relationship between radiotherapy and complications in general, but there was a trend towards more complications with immediate reconstructions. Autologous reconstruction was associated with fewer complications than heterologous, particularly with radiotherapy.
Discussion
Although previous studies suggest there is an association between radiotherapy and morbidity in post-mastectomy reconstruction, this study did not find any direct connection. The importance of distinguishing between complications at the donor and recipient sites stood out. Immediate reconstruction demonstrated a larger number of complications with radiotherapy, supporting the recommendation to postpone it. Autologous reconstruction was highlighted as the preferred option.
Conclusions
The study did not find a direct association between radiotherapy in post-mastectomy reconstruction patients and complications in general. However, it revealed a correlation between complications and heterologous techniques, emphasising the preference for autologous reconstructions.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
