经椎间孔腰椎内窥镜椎间盘切除术:对于L5-S1椎间孔及椎间孔外腰椎间盘突出症,我们是否应该放弃?一项前瞻性非随机研究和文献综述。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Stylianos Kapetanakis, Nikolaos Gkantsinikoudis
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引用次数: 0

摘要

目的:本研究旨在探讨经椎间孔腰椎内窥镜椎间盘切除术(TLED)对 L5-S1 腰椎间盘突出症(LDH)患者的临床疗效:本研究连续纳入了75名确诊为L5-S1椎间盘突出症(LDH)的患者。所有患者均接受了 TLED 治疗,并在两年的随访期内接受了评估。评估在术前、术后 6 周、3、6、12 和 24 个月进行。采用视觉模拟量表(分别适用于下肢疼痛--VAS-LP和腰背疼痛--VAS-BP)和短表36(SF-36)医疗健康调查问卷分别评估入选者的疼痛和健康相关生活质量(HRQoL):结果:未发现严重的围手术期并发症。所有研究指标的记录值均显示,6周时,临床和统计学上的疼痛明显减轻,3个月时改善程度较小,随后趋于稳定。VAS-LP和VAS-BP值在术后6个月达到平稳状态,而SF-36的所有参数在统计上都有明显改善,直到随访结束的2年:TLED是一种安全有效的技术,可减轻L5-S1 LDH患者的疼痛感并改善其HRQoL。然而,在手术经验不足的基础上,与患者和技术相关的特殊情况可能会限制其在这些患者中的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transforaminal lumbar endoscopic discectomy: should we abandon it for L5-S1 foraminal and extraforaminal lumbar disc herniations? A prospective non-randomised study and literature review.

Purpose: The aim of this study is to investigate the clinical outcomes of transforaminal lumbar endoscopic discectomy (TLED) in patients with L5-S1 lumbar disc herniation (LDH).

Materials and methods: Seventy-five consecutive individuals with diagnosed foraminal/extraforaminal L5-S1 LDH were included in this study. All patients underwent TLED, being subsequently evaluated in a 2-year follow-up period. Assessment was performed preoperatively and at 6 weeks and 3, 6, 12 and 24 months postoperatively. Visual Analogue Scale (distinctly applied for lower limb - VAS-LP and low back - VAS-BP pain) and Short-Form 36 (SF-36) Medical Health Survey Questionnaire were implemented to assess pain and health-related quality of life (HRQoL) of enrolled individuals, respectively.

Results: No major perioperative complications were observed. Recorded values of all studied indices were demonstrated to feature a clinically and statistically significant amelioration at 6 weeks, presenting lesser improvement at 3 months with subsequent stabilisation. VAS-LP and VAS-BP values were displayed to reach a plateau in 6 months postoperatively, whereas all parameters of SF-36 continued to present a statistically significant improvement until the end of follow-up at 2 years.

Conclusions: TLED represent a safe and efficient technique in terms of diminishing perceived pain and improving HRQoL in patients with L5-S1 LDHs. However, specific patient- and technique-related circumstances on the ground of low surgical experience may limit its effectiveness in these patients.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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