ZFP318 为记忆 B 细胞的成功提供动力

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2024-08-13 DOI:10.1016/j.immuni.2024.07.017

引用次数: 0

摘要

多样性是 B 细胞生物学的一个关键特征--从 BCR 重排到记忆 B 细胞的异质性。在本期《免疫》杂志上，Wang 等人的研究表明，锌指蛋白 ZFP318 支持某些记忆 B 细胞的线粒体健康，从而促进了再次挑战时的有效回忆。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ZFP318 fuels memory B cells for success

Diversity is a key feature of B cell biology—from BCR rearrangement to the heterogeneity of memory B cells. In this issue of Immunity, Wang et al. show that the zinc-finger protein ZFP318 supports mitochondrial health in certain memory B cells, thereby facilitating potent recall upon rechallenge.

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.