在突触中，EV 移动的是混乱，而不是信息。

IF 7.4 1区生物学 Q1 CELL BIOLOGY

Journal of Cell Biology Pub Date : 2024-09-02 Epub Date: 2024-08-13 DOI:10.1083/jcb.202408028

Marina N Bostelman, Heather T Broihier

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引用次数: 0

摘要

众所周知，细胞外囊泡具有细胞间信号传导的作用，但也可以简单地处理不需要的货物。在本期杂志中，Bostelman 和 Broihier 讨论了 Rodal 及其同事（https://doi.org/10.1083/jcb.202405025）的新研究，他们的研究驳斥了之前的研究，表明果蝇神经肌肉接头处的细胞外囊泡并非信号传导所必需，而很可能起到蛋白稳态的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EVs move messes, not messages, at the synapse.

Extracellular vesicles are known for intercellular signaling roles but can also serve to simply dispose of unwanted cargoes. In this issue, Bostelman and Broihier discuss new work from Rodal and colleagues (https://doi.org/10.1083/jcb.202405025) that refutes prior work by showing that extracellular vesicles at Drosophila neuromuscular junctions are not required for signaling and instead likely serve a proteostasis role.

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来源期刊

Journal of Cell Biology 生物-细胞生物学

CiteScore

12.60

自引率

2.60%

发文量

213

审稿时长

1 months

期刊介绍： The Journal of Cell Biology (JCB) is a comprehensive journal dedicated to publishing original discoveries across all realms of cell biology. We invite papers presenting novel cellular or molecular advancements in various domains of basic cell biology, along with applied cell biology research in diverse systems such as immunology, neurobiology, metabolism, virology, developmental biology, and plant biology. We enthusiastically welcome submissions showcasing significant findings of interest to cell biologists, irrespective of the experimental approach.