{"title":"有效控制大流行病的疫苗接种和运输干预战略","authors":"","doi":"10.1016/j.tranpol.2024.07.021","DOIUrl":null,"url":null,"abstract":"<div><p>The COVID-19 pandemic highlighted the pivotal role of transportation-related controls and vaccination in mitigating widespread infections. However, the substantial costs associated with these interventions necessitate a nuanced equilibrium between control measures and infection risks. This study, driven by the recognition of spatial heterogeneities in mobility networks and epidemic vulnerability, presents an optimal control framework for two control measures—vaccine distribution and transportation restrictions—within a metapopulation structure. The overarching goal is to minimize the total costs derived from the implementation of control measures and health and opportunity loss from infection. Our findings highlight the effectiveness of transportation control and vaccine distribution in reducing both total costs and infection rates. Notably, the efficacy of these control measures exhibits regional variations, and the simultaneous implementation of both measures emerges as the most effective and economically viable strategy. The synergy effect between vaccine distribution and transportation restrictions is also a key observation in our simulations, showcasing their complementary roles in pandemic control. By considering the spatial nuances of mobility networks and infection vulnerability, this framework provides a flexible and region-specific strategy to optimize the allocation of resources for pandemic control, ultimately striking a balance between efficacy and economic feasibility.</p></div>","PeriodicalId":48378,"journal":{"name":"Transport Policy","volume":null,"pages":null},"PeriodicalIF":6.3000,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0967070X24002233/pdfft?md5=7f588e4bdc33e80385995f76a340f242&pid=1-s2.0-S0967070X24002233-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Vaccination and transportation intervention strategies for effective pandemic control\",\"authors\":\"\",\"doi\":\"10.1016/j.tranpol.2024.07.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The COVID-19 pandemic highlighted the pivotal role of transportation-related controls and vaccination in mitigating widespread infections. However, the substantial costs associated with these interventions necessitate a nuanced equilibrium between control measures and infection risks. This study, driven by the recognition of spatial heterogeneities in mobility networks and epidemic vulnerability, presents an optimal control framework for two control measures—vaccine distribution and transportation restrictions—within a metapopulation structure. The overarching goal is to minimize the total costs derived from the implementation of control measures and health and opportunity loss from infection. Our findings highlight the effectiveness of transportation control and vaccine distribution in reducing both total costs and infection rates. Notably, the efficacy of these control measures exhibits regional variations, and the simultaneous implementation of both measures emerges as the most effective and economically viable strategy. The synergy effect between vaccine distribution and transportation restrictions is also a key observation in our simulations, showcasing their complementary roles in pandemic control. By considering the spatial nuances of mobility networks and infection vulnerability, this framework provides a flexible and region-specific strategy to optimize the allocation of resources for pandemic control, ultimately striking a balance between efficacy and economic feasibility.</p></div>\",\"PeriodicalId\":48378,\"journal\":{\"name\":\"Transport Policy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":6.3000,\"publicationDate\":\"2024-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S0967070X24002233/pdfft?md5=7f588e4bdc33e80385995f76a340f242&pid=1-s2.0-S0967070X24002233-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Transport Policy\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0967070X24002233\",\"RegionNum\":2,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ECONOMICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transport Policy","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0967070X24002233","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ECONOMICS","Score":null,"Total":0}
Vaccination and transportation intervention strategies for effective pandemic control
The COVID-19 pandemic highlighted the pivotal role of transportation-related controls and vaccination in mitigating widespread infections. However, the substantial costs associated with these interventions necessitate a nuanced equilibrium between control measures and infection risks. This study, driven by the recognition of spatial heterogeneities in mobility networks and epidemic vulnerability, presents an optimal control framework for two control measures—vaccine distribution and transportation restrictions—within a metapopulation structure. The overarching goal is to minimize the total costs derived from the implementation of control measures and health and opportunity loss from infection. Our findings highlight the effectiveness of transportation control and vaccine distribution in reducing both total costs and infection rates. Notably, the efficacy of these control measures exhibits regional variations, and the simultaneous implementation of both measures emerges as the most effective and economically viable strategy. The synergy effect between vaccine distribution and transportation restrictions is also a key observation in our simulations, showcasing their complementary roles in pandemic control. By considering the spatial nuances of mobility networks and infection vulnerability, this framework provides a flexible and region-specific strategy to optimize the allocation of resources for pandemic control, ultimately striking a balance between efficacy and economic feasibility.
期刊介绍:
Transport Policy is an international journal aimed at bridging the gap between theory and practice in transport. Its subject areas reflect the concerns of policymakers in government, industry, voluntary organisations and the public at large, providing independent, original and rigorous analysis to understand how policy decisions have been taken, monitor their effects, and suggest how they may be improved. The journal treats the transport sector comprehensively, and in the context of other sectors including energy, housing, industry and planning. All modes are covered: land, sea and air; road and rail; public and private; motorised and non-motorised; passenger and freight.