Shakil Ahmed Shaikh , Salma Farukh Memon , Naila Hajira Rahu , Keenjahr Rani Laghari , Zulfiqar Ali Laghari , Hanozia Shah
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The objective of the study is to observe the association of the ABO blood group with Lipid Profile and compare the association in different ABO blood groups.</p></div><div><h3>Methods</h3><p>This cross-sectional study includes 600 randomly selected subjects from different organizations of district Hyderabad including Universities, Colleges, Hospitals, students, faculty members, and their employees. This study was conducted from February 2021 to January 2022. Informed consent was obtained before the enrolment of volunteers. A structured questionnaire was used to obtain data related to sociodemographic characteristics. A detailed history was taken followed by a thorough clinical examination. All biochemical tests were performed using the blood analyzer and micro lab. Data obtained by structured questionnaire and anthropometric parameters were analyzed by SPSS version 20.0.</p></div><div><h3>Results</h3><p>In this study, the Overall B blood group was found more prevalent and similarly found in both males and females. We found Cholesterol higher in the O blood group and Rh-positive subjects.</p><p>Triglycerides were found higher in B and O and Rh Positive subjects. HDL was found to be higher in B and Rh-positive subjects. LDL was found higher in B and O and Rh Positive subjects. HDL was found to be higher in B and Rh-positive subjects. VLDL was found higher in both B and O AND Rh Positive subjects.</p></div><div><h3>Conclusion</h3><p>The evidence we collected is suggestive of the association of the ABO blood group with Lipid Profile.</p></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213398424002434/pdfft?md5=16d37c9a1ecf9ea86c40b0b7e87a1e1e&pid=1-s2.0-S2213398424002434-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Association of ABO blood group with lipid Profile in young adults of Hyderabad sindh\",\"authors\":\"Shakil Ahmed Shaikh , Salma Farukh Memon , Naila Hajira Rahu , Keenjahr Rani Laghari , Zulfiqar Ali Laghari , Hanozia Shah\",\"doi\":\"10.1016/j.cegh.2024.101746\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background and objectives</h3><p>Dyslipidemia is one of the major predictors of cardiovascular disease. Cardiovascular diseases are the major cause of morbidity and mortality in developed as well as developing countries around the world. Cardiovascular diseases are becoming more prevalent in Pakistan and are the major cause of mortality in Pakistan. The number of studies previously carried out on ABO blood group association has been reported with many diseases including cancer, ulcer, diabetes, and hypertension. However, no study has previously reported an association of blood groups in apparently normal subjects. The objective of the study is to observe the association of the ABO blood group with Lipid Profile and compare the association in different ABO blood groups.</p></div><div><h3>Methods</h3><p>This cross-sectional study includes 600 randomly selected subjects from different organizations of district Hyderabad including Universities, Colleges, Hospitals, students, faculty members, and their employees. This study was conducted from February 2021 to January 2022. 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引用次数: 0
摘要
背景和目标血脂异常是心血管疾病的主要预测因素之一。无论是在发达国家还是发展中国家，心血管疾病都是发病和死亡的主要原因。心血管疾病在巴基斯坦越来越普遍，也是巴基斯坦人死亡的主要原因。之前有许多关于 ABO 血型与癌症、溃疡、糖尿病和高血压等多种疾病相关的研究报告。然而，此前还没有研究报告称血型与表面上正常的受试者有关。本研究的目的是观察 ABO 血型与血脂谱的关系，并比较不同 ABO 血型之间的关系。本横断面研究包括从海德拉巴地区不同机构（包括大学、学院、医院、学生、教职员工及其雇员）随机抽取的 600 名受试者。研究时间为 2021 年 2 月至 2022 年 1 月。在招募志愿者之前，已征得他们的知情同意。采用结构化问卷调查的方式获取与社会人口特征相关的数据。详细询问病史后进行全面的临床检查。所有生化检验均使用血液分析仪和微型实验室进行。通过结构式问卷调查获得的数据和人体测量参数由 SPSS 20.0 版进行分析。我们发现胆固醇在 O 型血和 Rh 阳性受试者中较高，甘油三酯在 B 型血和 O 型血及 Rh 阳性受试者中较高。高密度脂蛋白在 B 型血和 Rh 阳性受试者中较高。B型、O型和Rh阳性受试者的低密度脂蛋白较高。B型和Rh阳性受试者的高密度脂蛋白较高。结论 我们收集的证据表明，ABO 血型与血脂谱有关。
Association of ABO blood group with lipid Profile in young adults of Hyderabad sindh
Background and objectives
Dyslipidemia is one of the major predictors of cardiovascular disease. Cardiovascular diseases are the major cause of morbidity and mortality in developed as well as developing countries around the world. Cardiovascular diseases are becoming more prevalent in Pakistan and are the major cause of mortality in Pakistan. The number of studies previously carried out on ABO blood group association has been reported with many diseases including cancer, ulcer, diabetes, and hypertension. However, no study has previously reported an association of blood groups in apparently normal subjects. The objective of the study is to observe the association of the ABO blood group with Lipid Profile and compare the association in different ABO blood groups.
Methods
This cross-sectional study includes 600 randomly selected subjects from different organizations of district Hyderabad including Universities, Colleges, Hospitals, students, faculty members, and their employees. This study was conducted from February 2021 to January 2022. Informed consent was obtained before the enrolment of volunteers. A structured questionnaire was used to obtain data related to sociodemographic characteristics. A detailed history was taken followed by a thorough clinical examination. All biochemical tests were performed using the blood analyzer and micro lab. Data obtained by structured questionnaire and anthropometric parameters were analyzed by SPSS version 20.0.
Results
In this study, the Overall B blood group was found more prevalent and similarly found in both males and females. We found Cholesterol higher in the O blood group and Rh-positive subjects.
Triglycerides were found higher in B and O and Rh Positive subjects. HDL was found to be higher in B and Rh-positive subjects. LDL was found higher in B and O and Rh Positive subjects. HDL was found to be higher in B and Rh-positive subjects. VLDL was found higher in both B and O AND Rh Positive subjects.
Conclusion
The evidence we collected is suggestive of the association of the ABO blood group with Lipid Profile.
期刊介绍：
Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
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