基于诱导多能干细胞的毛囊发育和再生方法

IF 3.4 3区环境科学与生态学 Q3 CELL & TISSUE ENGINEERING

Regenerative Therapy Pub Date : 2024-06-01 DOI:10.1016/j.reth.2024.07.005

Poornima Sivamani , Ramya Lakshmi Rajendran , Prakash Gangadaran , Byeong-Cheol Ahn

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引用次数: 0

摘要

由于脱发是许多人共同关心的问题，人们对毛囊再生疗法的潜力进行了广泛研究。诱导多能干细胞（iPSC）是毛囊再生的一个很有前景的途径。这篇综述探讨了目前基于 iPSC 的方法，并重点介绍了它们在毛发修复中的潜在应用和挑战。文中还讨论了 iPSC 技术的原理、iPSC 向毛囊前体细胞的分化以及对毛囊再生的潜在临床意义。这篇关于 iPSC 及其应用的综述旨在帮助我们了解 iPSC 在毛发修复中的作用以及未来潜在的治疗应用。

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An induced pluripotent stem cell-based approach for hair follicle development and regeneration

Because hair loss is a common concern for many individuals, potential regenerative therapies of hair follicles have been extensively researched. Induced pluripotent stem cells (iPSCs) are a promising avenue for hair follicle regeneration. This review explores current iPSC-based approaches and highlights their potential applications and challenges in hair restoration. The principles of iPSC technology, iPSC differentiation into hair follicle precursor cells, and potential clinical implications for hair follicle regeneration are also discussed. This overview of iPSCs and their applications aims to contribute to our understanding of their role in hair restoration and potential future therapeutic applications.

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来源期刊

Regenerative Therapy Engineering-Biomedical Engineering

CiteScore

6.00

自引率

2.30%

发文量

106

审稿时长

49 days

期刊介绍： Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine. Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.