来自拟南芥的一种新的裂环原紫罗兰烷类倍半萜和前酰基芳香化合物

IF 1.3 4区生物学 Q4 CHEMISTRY, MEDICINAL

Phytochemistry Letters Pub Date : 2024-07-26 DOI:10.1016/j.phytol.2024.07.008

Xin-Meng Zhai, Lu-Lu Wang, Ning Li, Fu-Cai Ren

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引用次数: 0

摘要

从鸢尾果实的乙醇提取物中分离出了一种迄今未知的原鸢尾烷类倍半萜--8β-羟基表萜烯 D（1），以及两种新型炔基芳香化合物，即鸢尾素 A 和 B（2-3）。通过大量的光谱数据分析以及实验和计算电子圆二色性数据的比较，确定了它们的结构。化合物 2 和 3 是异戊烯基连接到芳香环侧链而不是直接连接到芳香环上的罕见例子，分别含有琥珀酰亚胺和炔基段。提出了化合物 2 和 3 的合理生物合成途径，并可能存在独特的芳香族前炔基转移酶。

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A new split-ring protoilludane-type sesquiterpenoid and prenylated aromatic compounds from Coriolopsis trogii

One hitherto unknown protoilludane-type sesquiterpene, 8β-hydroxyepicoterpene D (1), along with two novel prenylated aromatic compounds, namely coriolopsisins A and B (2–3), were isolated from the ethanol extract of Coriolopsis trogii fruit body. Their structures were determined through extensive spectroscopic data analysis and comparison of experimental and calculated electronic circular dichroism data. Compounds 2 and 3 are rare examples in which the isopentenyl group is attached to the side chain of the aromatic ring rather than directly to the aromatic ring, containing succinimide and alkynyl segments, respectively. Plausible biosynthetic pathways of compounds 2 and 3 are proposed and unique aromatic prenyltransferases may exist.

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来源期刊

Phytochemistry Letters 生物-生化与分子生物学

CiteScore

3.00

自引率

11.80%

发文量

190

审稿时长

34 days

期刊介绍： Phytochemistry Letters invites rapid communications on all aspects of natural product research including: • Structural elucidation of natural products • Analytical evaluation of herbal medicines • Clinical efficacy, safety and pharmacovigilance of herbal medicines • Natural product biosynthesis • Natural product synthesis and chemical modification • Natural product metabolism • Chemical ecology • Biotechnology • Bioassay-guided isolation • Pharmacognosy • Pharmacology of natural products • Metabolomics • Ethnobotany and traditional usage • Genetics of natural products Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.