心脏骤停后左心室射血分数与出院存活率有关

IF 2.1 Q3 CRITICAL CARE MEDICINE

Resuscitation plus Pub Date : 2024-08-10 DOI:10.1016/j.resplu.2024.100737

Kanjit Leungsuwan, Kory R. Heier, Olivia Henderson, Karam Ayoub, Talal Alnabelsi, Emily Slade, Vedant A. Gupta

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引用次数: 0

摘要

背景心脏骤停后左心室射血分数（LVEF）是常规评估指标，但其意义尚不清楚。本研究旨在评估心脏骤停后左心室射血分数（LVEF）与出院存活率之间的关系。方法在这项回顾性队列研究中，纳入了 2012 年 1 月至 2015 年 9 月期间在我们三级医疗中心发生的所有院内和院外心脏骤停患者。研究收集了基线人口统计学数据、临床数据、骤停特征和所采取的干预措施。对心脏骤停后最早的超声心动图进行审查，并记录 LVEF。主要结果是出院后的存活率。结果共有 736 名患者参与分析（平均年龄 58 岁，44% 为女性）。15%为院外心脏骤停（24%为可电击心律）。调整协变量后，LVEF < 30% 的患者出院存活率比 LVEF ≥ 52% 的患者低 36% (p = 0.014)。结论心脏骤停后，初始 LVEF < 30% 的患者出院存活率明显较低。

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Post cardiac arrest left ventricular ejection fraction associated with survival to discharge

Background

Post cardiac arrest left ventricular ejection fraction (LVEF) is routinely assessed, but the implications of this are unknown. This study aimed to assess the association between post cardiac arrest LVEF and survival to hospital discharge.

Methods

In this retrospective cohort study, all in-hospital and out of hospital cardiac arrests at our tertiary care center between January 2012 and September 2015 were included. Baseline demographics, clinical data, characteristics of the arrest, and interventions performed were collected. Earliest post cardiac arrest echocardiograms were reviewed with LVEF documented. The primary outcome was survival to discharge.

Results

A total of 736 patients were included in the analysis (mean age 58 years, 44% female). 15% were out of hospital cardiac arrest (24% shockable rhythm). After adjusting for covariates, patients with LVEF < 30% had 36% lower odds of surviving to hospital discharge than those with LVEF $\geq$ 52% (p = 0.014). Shockable initial rhythm and targeted temperature management were associated with improved survival.

Conclusion

After a cardiac arrest, an initial LVEF < 30% is associated with significantly lower odds of survival to hospital discharge.

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来源期刊

Resuscitation plus Critical Care and Intensive Care Medicine, Emergency Medicine

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

52 days