一名神经纤维瘤病 1 患者的全膝关节置换术

IF 1.5 Q3 ORTHOPEDICS
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引用次数: 0

摘要

神经纤维瘤病 1(NF1)是一种罕见的遗传综合征,会导致神经纤维瘤的发生,并增加恶性肿瘤(包括恶性周围神经鞘瘤)的风险。NF1患者通常还有其他骨科表现,包括身材矮小、骨质增生和发育不良。一名 47 岁的患者有 NF1 和右下肢多发性神经纤维瘤病史,右膝盖出现严重外翻畸形、不稳定和骨关节炎,使日常生活受到影响。随着时间的推移,神经纤维瘤的形成使患者丧失了本体感觉,右膝盖可能也失去了一些感觉,从而导致右膝盖夏科关节病并继发骨关节炎。术前检查包括膝关节磁共振成像,以确认没有恶性肿瘤,以及模板设计,以确保患者可以接受标准的植入物尺寸。手术使用了骨水泥柄铰链膝关节假体,进行了初级全膝关节置换术。术后 6 个月,患者的疼痛和生活质量得到了显著改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Total Knee Arthroplasty in a Patient With Neurofibromatosis 1

Neurofibromatosis 1 (NF1) is a rare genetic syndrome that leads to the development of neurofibromas and increases the risk of malignancy, including malignant peripheral nerve sheath tumors. Patients with NF1 often have other orthopaedic manifestations, including short stature, osteopenia, and dysplasia. A 47-year-old patient with a history of NF1 and multiple neurofibromas of the right lower extremity presented with a severe valgus deformity, instability, and osteoarthritis of the right knee that was debilitating to daily life. Over time, the patient lost proprioception and potentially some sensation to the right knee with neurofibroma formation, leading to the development of Charcot arthropathy of the right knee with secondary osteoarthritis. The preoperative workup consisted of a magnetic resonance imaging of the knee to confirm no malignancy was present and templating to ensure the standard implant size was amenable for the patient. A primary total knee arthroplasty was performed with a cemented-stemmed hinged knee implant. At 6 months post-surgery, the patient had a dramatic improvement in her pain and quality of life.

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来源期刊
Arthroplasty Today
Arthroplasty Today Medicine-Surgery
CiteScore
2.90
自引率
0.00%
发文量
258
审稿时长
40 weeks
期刊介绍: Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.
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