在烧伤患者中使用整合真皮再生模板：意大利专家共识德尔菲研究

IF 3.2 3区医学 Q2 CRITICAL CARE MEDICINE

Burns Pub Date : 2024-08-08 DOI:10.1016/j.burns.2024.08.002

Giuseppe Giudice , Rosario Ranno , Giuseppe Lombardo , Antonio Di Lonardo , Giuseppe Perniciaro , Maria Alma Posadinu , Davide Melandri , Roberto D'Alessio , Franz Baruffaldi Preis , Marcello Zamparelli , Daniela Risso , Giuseppe Minunni , Enrico Pinzauti , Stefano Merelli , Maurizio Governa , Giulio Maggio , Pasquale Tedeschi

{"title":"在烧伤患者中使用整合真皮再生模板：意大利专家共识德尔菲研究","authors":"Giuseppe Giudice , Rosario Ranno , Giuseppe Lombardo , Antonio Di Lonardo , Giuseppe Perniciaro , Maria Alma Posadinu , Davide Melandri , Roberto D'Alessio , Franz Baruffaldi Preis , Marcello Zamparelli , Daniela Risso , Giuseppe Minunni , Enrico Pinzauti , Stefano Merelli , Maurizio Governa , Giulio Maggio , Pasquale Tedeschi","doi":"10.1016/j.burns.2024.08.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Burn injuries pose significant challenges in healthcare, with Integra dermal regeneration template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra in managing burn wounds.</div></div><div><h3>Methods</h3><div>Panelists employed a modified Delphi technique to assess agreement and provide feedback on 81 initial statements covering various aspects of Integra DRT application in burn wound care over three subsequent rounds. This study was endorsed by the Italian Society of Burn Surgery (SIUST).</div></div><div><h3>Results</h3><div>Fourteen heads of burn unit departments participated in the Delphi process. At the end of the third round and subsequent discussion on the final statement list, the panel achieved consensus on 24 statements shaping recommendations for Integra application across various aspects, including wound bed preparation, acellular dermal matrix application, definitive coverage, and complication management.</div></div><div><h3>Conclusion</h3><div>The resultant 24 finalized statements from this Italian consensus offer a comprehensive and practical framework for employing Integra DRT in burn patient care. Reflective of specific Italian expertise and practice, these recommendations supplement and refine existing literature, serving as a dynamic guide subject to periodic updates aligned with evolving evidence and experience in the field of burn surgery.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107236"},"PeriodicalIF":3.2000,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Use of Integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study\",\"authors\":\"Giuseppe Giudice , Rosario Ranno , Giuseppe Lombardo , Antonio Di Lonardo , Giuseppe Perniciaro , Maria Alma Posadinu , Davide Melandri , Roberto D'Alessio , Franz Baruffaldi Preis , Marcello Zamparelli , Daniela Risso , Giuseppe Minunni , Enrico Pinzauti , Stefano Merelli , Maurizio Governa , Giulio Maggio , Pasquale Tedeschi\",\"doi\":\"10.1016/j.burns.2024.08.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Burn injuries pose significant challenges in healthcare, with Integra dermal regeneration template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra in managing burn wounds.</div></div><div><h3>Methods</h3><div>Panelists employed a modified Delphi technique to assess agreement and provide feedback on 81 initial statements covering various aspects of Integra DRT application in burn wound care over three subsequent rounds. This study was endorsed by the Italian Society of Burn Surgery (SIUST).</div></div><div><h3>Results</h3><div>Fourteen heads of burn unit departments participated in the Delphi process. At the end of the third round and subsequent discussion on the final statement list, the panel achieved consensus on 24 statements shaping recommendations for Integra application across various aspects, including wound bed preparation, acellular dermal matrix application, definitive coverage, and complication management.</div></div><div><h3>Conclusion</h3><div>The resultant 24 finalized statements from this Italian consensus offer a comprehensive and practical framework for employing Integra DRT in burn patient care. Reflective of specific Italian expertise and practice, these recommendations supplement and refine existing literature, serving as a dynamic guide subject to periodic updates aligned with evolving evidence and experience in the field of burn surgery.</div></div>\",\"PeriodicalId\":50717,\"journal\":{\"name\":\"Burns\",\"volume\":\"50 9\",\"pages\":\"Article 107236\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2024-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Burns\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0305417924002390\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Burns","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0305417924002390","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

烧伤给医疗保健带来了巨大挑战，而 Integra 皮肤再生模板（DRT）则成为促进伤口愈合和恢复的重要解决方案。尽管对其技术用途和应用还没有达成明确的共识。我们召集了一个由 14 位烧伤专家组成的小组，旨在就 Integra® 在烧伤伤口管理中的应用和使用达成共识。小组成员采用改良的德尔菲技术对 81 项初步声明进行了评估，这些声明涵盖了 Integra DRT 在烧伤创面护理中应用的各个方面，并在随后的三轮讨论中就这些声明达成了一致并提供了反馈意见。这项研究得到了意大利烧伤外科协会（SIUST）的支持。14 位烧伤科主任参与了德尔菲过程。在第三轮讨论结束并对最终声明列表进行讨论后，专家小组就 24 项声明达成了共识，这些声明对 Integra® 的应用提出了多方面的建议，包括伤口床准备、ADM 应用、最终覆盖和并发症处理。这次意大利共识会议最终确定的 24 项声明为在烧伤患者护理中使用 Integra® 皮肤再生模板提供了一个全面而实用的框架。这些建议反映了意大利特定的专业知识和实践，是对现有文献的补充和完善，是根据烧伤外科领域不断发展的证据和经验定期更新的动态指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Use of Integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study

Introduction

Burn injuries pose significant challenges in healthcare, with Integra dermal regeneration template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra in managing burn wounds.

Methods

Panelists employed a modified Delphi technique to assess agreement and provide feedback on 81 initial statements covering various aspects of Integra DRT application in burn wound care over three subsequent rounds. This study was endorsed by the Italian Society of Burn Surgery (SIUST).

Results

Fourteen heads of burn unit departments participated in the Delphi process. At the end of the third round and subsequent discussion on the final statement list, the panel achieved consensus on 24 statements shaping recommendations for Integra application across various aspects, including wound bed preparation, acellular dermal matrix application, definitive coverage, and complication management.

Conclusion

The resultant 24 finalized statements from this Italian consensus offer a comprehensive and practical framework for employing Integra DRT in burn patient care. Reflective of specific Italian expertise and practice, these recommendations supplement and refine existing literature, serving as a dynamic guide subject to periodic updates aligned with evolving evidence and experience in the field of burn surgery.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Burns 医学-皮肤病学

CiteScore

4.50

自引率

18.50%

发文量

304

审稿时长

72 days

期刊介绍： Burns aims to foster the exchange of information among all engaged in preventing and treating the effects of burns. The journal focuses on clinical, scientific and social aspects of these injuries and covers the prevention of the injury, the epidemiology of such injuries and all aspects of treatment including development of new techniques and technologies and verification of existing ones. Regular features include clinical and scientific papers, state of the art reviews and descriptions of burn-care in practice. Topics covered by Burns include: the effects of smoke on man and animals, their tissues and cells; the responses to and treatment of patients and animals with chemical injuries to the skin; the biological and clinical effects of cold injuries; surgical techniques which are, or may be relevant to the treatment of burned patients during the acute or reconstructive phase following injury; well controlled laboratory studies of the effectiveness of anti-microbial agents on infection and new materials on scarring and healing; inflammatory responses to injury, effectiveness of related agents and other compounds used to modify the physiological and cellular responses to the injury; experimental studies of burns and the outcome of burn wound healing; regenerative medicine concerning the skin.