通过纳米孔电穿孔技术进行 DNA 增强型细胞内蛋白质输送

IF 17.3 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Matter Pub Date : 2024-08-07 DOI:10.1016/j.matt.2024.06.009

Matthew Lee Manion , Albert Tianxiang Liu

引用次数: 0

摘要

细胞工程前景的核心是为细胞装载一系列外源货物，并在运送过程中保持货物功能的方法。美国西北大学的一个跨学科团队提出了一种局部电穿孔技术，该技术使用纳米孔膜，可以在保持功能的情况下高效地输送大分子蛋白质。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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DNA augmented intracellular protein delivery via nanopore electroporation

Core to the prospects of cellular engineering are methods to load cells with a range of exogenous cargo that maintain cargo faculties upon delivery. An interdisciplinary team at Northwestern University presents a localized version of electroporation, using nanopore membranes, that can deliver large proteins efficiently with preserved functionality.

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来源期刊

Matter MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

26.30

自引率

2.60%

发文量

367

期刊介绍： Matter, a monthly journal affiliated with Cell, spans the broad field of materials science from nano to macro levels,covering fundamentals to applications. Embracing groundbreaking technologies,it includes full-length research articles,reviews, perspectives,previews, opinions, personnel stories, and general editorial content. Matter aims to be the primary resource for researchers in academia and industry, inspiring the next generation of materials scientists.