来自槟榔内生真菌 Alternaria sp.

IF 0.8 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI:10.1007/s10600-024-04413-4

Wu Ruan, Qing-Yun Ma, Jiao-Cen Guo, Qing-Yi Xie, Li Yang, Hao-Fu Dai, You-Geng Wu, You-Xing Zhao

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引用次数: 0

摘要

从槟榔内生真菌 Alternaria sp. RW-AL 中分离出了一种新的环肽交替灵 A（1），以及七种已知化合物：交替醇（2）、交替醇硫酸化衍生物（3）、交替醇甲醚（4）、altenuene（5）、2,5-二甲基-7-羟基色酮（6）、二交替醇 A（7）、异交替醇（8）。通过一维和二维核磁共振光谱以及 HR-ESI-MS 分析，阐明了 1 的结构。化合物 1、4 和 5 对金黄色葡萄球菌 ATCC 6538 和枯草芽孢杆菌 ATCC 6633 具有明确的抗菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL

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A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL

A new cyclic peptide alternarin A (1), along with seven known compounds, alternariol (2), sulfated derivative of alternariol (3), alternariol methyl ether (4), altenuene (5), 2,5-dimethyl-7-hydroxychromone (6), diaporthein A (7), isopterocarpolone (8), were isolated from the betel nut endophytic fungus Alternaria sp. RW-AL. The structure of 1 was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds 1, 4, and 5 showed definite antibacterial activities against Staphylococcus aureus ATCC 6538 and Bacillus subtilis ATCC 6633.

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.