来自 Persea americana 的新查尔酮衍生物及其抗酪氨酸酶活性

IF 0.8 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI:10.1007/s10600-024-04399-z

Parinuch Chumkaew, Saysunee Jumrat, Yutthapong Pianroj

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引用次数: 0

摘要

从 Persea americana Mill.的种子中分离出了一种新的查尔酮衍生物 Caneeracone A（1）以及三种已知化合物（2-4）。(牛油果）的种子中分离出来。这些化合物的结构是通过光谱方法（包括一维和二维核磁共振实验）确定的。化合物 1 具有很强的酪氨酸酶活性，其 IC50 值为 38.29 μM。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

New Chalcone Derivative from Persea americana and Its Anti-Tyrosinase Activity

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New Chalcone Derivative from Persea americana and Its Anti-Tyrosinase Activity

Caneeracone A (1), a new chalcone derivative, together with three known compounds (2–4), was isolated from the seeds of Persea americana Mill. (buccaneer avocado). The structures of these compounds were established by spectroscopic methods including 1D and 2D NMR experiments. Compound 1 exhibited a potent tyrosinase activity with an IC₅₀ of 38.29 μM.

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.