来自 Glochidion eriocarpum 的三萜类化合物

IF 0.8 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2024-08-07 DOI:10.1007/s10600-024-04405-4

Jin-Ni Tan, Chun-Hua Lai, Wei Wei, Qin-Gang Tan

{"title":"来自 Glochidion eriocarpum 的三萜类化合物","authors":"Jin-Ni Tan, Chun-Hua Lai, Wei Wei, Qin-Gang Tan","doi":"10.1007/s10600-024-04405-4","DOIUrl":null,"url":null,"abstract":"Six lupane triterpenoids (1–6), including an undescribed one, 3,23-di-O-isopropylidene-lup-20(29)-ene (1), along with two oleane triterpenoids (7, 8), were isolated from the Zhuang ethnic medicinal plant Glochidion eriocarpum. Their structures were identified based on comprehensive NMR, MS, and physiochemical data analysis. Compounds 2, 7, and 8 significantly inhibited the production of nitride oxide (NO) of the LPS-induced RAW 264.7 cells, which may be attributed to the anti-inflammatory activity of this plant.","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Triterpenoids from Glochidion eriocarpum\",\"authors\":\"Jin-Ni Tan, Chun-Hua Lai, Wei Wei, Qin-Gang Tan\",\"doi\":\"10.1007/s10600-024-04405-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Six lupane triterpenoids (1–6), including an undescribed one, 3,23-di-O-isopropylidene-lup-20(29)-ene (1), along with two oleane triterpenoids (7, 8), were isolated from the Zhuang ethnic medicinal plant Glochidion eriocarpum. Their structures were identified based on comprehensive NMR, MS, and physiochemical data analysis. Compounds 2, 7, and 8 significantly inhibited the production of nitride oxide (NO) of the LPS-induced RAW 264.7 cells, which may be attributed to the anti-inflammatory activity of this plant.\",\"PeriodicalId\":514,\"journal\":{\"name\":\"Chemistry of Natural Compounds\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry of Natural Compounds\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s10600-024-04405-4\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry of Natural Compounds","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10600-024-04405-4","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}

引用次数: 0

摘要

研究人员从壮族药用植物钩吻中分离出六种羽扇豆三萜类化合物（1-6），其中包括一种未曾描述过的3,23-di-O-异亚丙基-lup-20(29)-ene（1），以及两种油烷三萜类化合物（7，8）。根据全面的核磁共振、质谱和理化数据分析，确定了它们的结构。化合物 2、7 和 8 能明显抑制 LPS 诱导的 RAW 264.7 细胞产生氮氧化物（NO），这可能与该植物的抗炎活性有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Triterpenoids from Glochidion eriocarpum

查看原文本刊更多论文

Triterpenoids from Glochidion eriocarpum

Six lupane triterpenoids (1–6), including an undescribed one, 3,23-di-O-isopropylidene-lup-20(29)-ene (1), along with two oleane triterpenoids (7, 8), were isolated from the Zhuang ethnic medicinal plant Glochidion eriocarpum. Their structures were identified based on comprehensive NMR, MS, and physiochemical data analysis. Compounds 2, 7, and 8 significantly inhibited the production of nitride oxide (NO) of the LPS-induced RAW 264.7 cells, which may be attributed to the anti-inflammatory activity of this plant.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.