一名滤泡性淋巴瘤患者接受 CD3/CD20 双特异性抗体治疗后出现播散性分枝杆菌复合体感染

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2024-08-08 DOI:10.1093/ofid/ofae460

J. Little, Rocio M Hurtado, Nicholas Boire, Lindsey R. Baden, A. Laga, Ann W Silk, Caron A Jacobson

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引用次数: 0

摘要

感染仍然是双特异性抗体（BsAb）治疗后的一个主要问题，但在关键试验中并没有得到很好的描述。我们介绍了第一例有据可查的典型但罕见的机会性感染病例，即在接受双特异性抗体治疗的患者中发生的播散性复合分枝杆菌感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Disseminated Mycobacterium avium complex Infection following CD3/CD20 Bispecific Antibody Therapy in a Patient with Follicular Lymphoma

Infections remain a major concern following bispecific antibody (BsAb) therapy but are not well described in pivotal trials. We present the first well documented case of a classic but rare opportunistic infection, disseminated Mycobacterium avium complex, in a patient receiving BsAb therapy.

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.