颅内动静脉畸形的血液动力学评估:治疗前和治疗后的二维相位对比 MRI 测量。

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Acta radiologica open Pub Date : 2024-08-08 eCollection Date: 2024-08-01 DOI:10.1177/20584601241269608
Maria Correia de Verdier, Elisabeth Ronne-Engström, Ljubisa Borota, Johan Wikström
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引用次数: 0

摘要

背景:动静脉畸形(AVM)的供血动脉会出现血流动力学变化。相位对比 MRI(PC-MRI)可获取血管的血流动力学信息。目的:评估 PC-MRI 测量的动静脉畸形供血动脉的血流和血流速度,并将这些测量结果与健康对照组的相应测量结果进行比较。材料和方法:在 3 T 下使用二维 PC-MRI 测量颅内动静脉畸形患者进动脉的最高流量(HF)、最低流量(LF)、平均流量(MF)、收缩峰值速度(PSV)、舒张末期速度(EDV)和平均速度(MV)。高于健康人群第 95 百分位数的值被归类为病理值。使用三维飞行时间磁共振血管造影测量瘤巢体积:结果:10 名确诊为 AVM 的患者接受了 PC-MRI 检查。结果:10 名确诊为 AVM 的患者接受了 PC-MRI 检查,其中 3 名患者在治疗后还接受了 PC-MRI 随访。瘤巢大于或等于 5.7 立方厘米的五名受试者均出现了病理速度(PSV、EDV 和 MV),但并非所有受试者都出现了病理血流值,即三名受试者出现了病理 HF,两名受试者出现了病理 LF,两名受试者出现了病理 MF。治疗后,血流和血流速度(所有测量参数)均有所下降。治疗后,与健康对照组相比,血流速度(PSV、EDV 和 MV)不再异常:结论:大面积动静脉畸形瘤巢患者的血流速度呈病态,但血流增加的一致性较差。治疗后,血流速度恢复正常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemodynamic evaluation of intracranial arteriovenous malformations: Pre- and post-treatment 2D phase-contrast MRI measurements.

Background: Hemodynamic changes are seen in the feeding arteries of arteriovenous malformations (AVMs). Phase-contrast MRI (PC-MRI) enables the acquisition of hemodynamic information from blood vessels. There is insufficient knowledge on which flow or velocity parameter best discriminates AVMs from healthy subjects.

Purpose: To evaluate PC-MRI-measured flow and velocity in feeding arteries of AVMs before and, when possible, also after treatment and to compare these measurements to corresponding measurements in healthy controls.

Materials and methods: Highest flow (HF), lowest flow (LF), mean flow (MF), peak systolic velocity (PSV), end-diastolic velocity (EDV), and mean velocity (MV) were measured in feeding arteries in patients with intracranial AVMs using 2D PC-MRI at 3 T. Measurements were compared to previously reported values in healthy individuals. Values in patients above the 95th percentile in the healthy cohort were categorized as pathological. Nidus volume was measured using 3D time-of-flight MR angiography.

Results: Ten patients with diagnosed AVMs were examined with PC-MRI. Among these, three patients also underwent follow-up PC-MRI after treatment. Pathological velocities (PSV, EDV, and MV) were seen in all five subjects with a nidus larger or equal to 5.7 cm3, whereas pathological flow values were not seen in all, that is, pathologic HF in three, pathologic LF in two, and pathologic MF in two. After treatment, there was a decrease in flow and velocity (all measured parameters). After treatment, velocities (PSV, EDV, and MV) were no longer abnormal compared to healthy controls.

Conclusion: Patients with a large AVM nidus show pathological velocities, but less consistent flow increases. Following treatment, velocities normalize.

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