尸体中 SARS-CoV-2 病毒 RNA 的 RT-PCR 检测结果及处理者感染病毒的风险。

IF 1.5 Q3 CRITICAL CARE MEDICINE
Bandita Panda, Nipa Singh, Gyanraj Singh, A Raj K Patro, Ambika P Mohanty, Pradeep K Patnaik, Ramnath Misra
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引用次数: 0

摘要

在疫情爆发期间,医院工作人员和处理 COVID-19 感染尸体的家属提出了一个常见的研究问题:"COVID-19 阳性尸体是否携带 SARS-CoV-2 病毒 RNA?"有一些研究结果被报道,但由于缺乏适当的研究结果,这个问题仍然没有答案。本研究计划观察尸体将病毒传播给处理人员的风险。本研究对 2021-2022 年期间在 COVID-ICU 死亡的 54 具尸体(经 RT-PCR 诊断为 SARS-CoV-2 阳性)进行了试点研究。研究人員在 54 具屍體死亡後一小時內抽取其皮膚拭抹樣本,並從處理人員的手套中抽取 54 個樣本進行 RT-PCR 測試。RT-PCR測試結果顯示,屍體感染SARS-CoV-2的風險為50%,而處理人員在處理屍體時感染SARS-CoV-2的風險則為7%,風險極低。在经过长时间感染后死亡的病例中,SARS-CoV-2 的存活率很高。根据 RT-PCR 结果和数据分析,这项研究的结论是,SARS-CoV-2 从尸体传播给处理人员的风险很小,但尸体中的 SARS-CoV-2 存活率很高。这一事实对从事殡葬活动的人、验尸人员和处理尸体的医院工作人员很有帮助:Panda B、Singh N、Singh G、Patro ARK、Mohanty AP、Patnaik PK等:尸体中SARS-CoV-2病毒RNA的RT-PCR结果及病毒传播给处理人员的风险。Indian J Crit Care Med 2024;28(6):614-616.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RT-PCR Result of SARS-CoV-2 Viral RNA in Cadavers and Viral Transmission Risk to Handlers.

During the onset of the pandemic, a common research question was asked by the hospital staff, and family members who were handling COVID-19-infected cadavers, "does COVID-19-positive dead body harbor SARS-CoV-2 viral RNA?" Several research findings were reported but due to the lack of proper research findings, the question remained unanswered. The present study was planned to observe the virus transmission risk from cadavers to the handlers. A pilot study was conducted on 54 cadavers who died in COVID-ICU (SARS-CoV-2-positive diagnosed by RT-PCR) during 2021-2022. Skin swab sample from 54 dead bodies and 54 glove samples of handlers were taken within 1 hour of death for the RT-PCR test. Viability results from RT-PCR show that the infection risk was 50% in cadavers, whereas the transmission risk to handlers while handling was 7%, which is minimal. The SARS-CoV-2 viability was high in cases of those died after a long time of infection. Based on the RT-PCR result and data analysis the interpretation of the study was that the SARS-CoV-2 transmission risk from dead bodies to the handlers is minimal but the SARS-CoV-2 viability persists in the cadavers. This fact is helpful for the people who will conduct funeral activities, autopsy staff, and hospital staff handling dead bodies.

How to cite this article: Panda B, Singh N, Singh G, Patro ARK, Mohanty AP, Patnaik PK, et al. RT-PCR Result of SARS-CoV-2 Viral RNA in Cadavers and Viral Transmission Risk to Handlers. Indian J Crit Care Med 2024;28(6):614-616.

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来源期刊
CiteScore
3.50
自引率
10.00%
发文量
299
期刊介绍: Indian Journal of Critical Care Medicine (ISSN 0972-5229) is specialty periodical published under the auspices of Indian Society of Critical Care Medicine. Journal encourages research, education and dissemination of knowledge in the fields of critical and emergency medicine.
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