{"title":"亚洲儿童与气单胞菌相关腹泻的系统回顾和元分析。","authors":"Hamid Sadeghi, Masoumeh Aslanimehr, Farhad Nikkhahi, Roya Safari, Majid Vafaie, Saeideh Gholamzadeh Khoei","doi":"10.1089/sur.2024.090","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Background:</i></b> Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. <i>Aeromonas</i> is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of <i>Aeromonas</i> as an agent in the causation of diarrhea in Asian children. <b><i>Methods:</i></b> We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found <i>Aeromonas</i> in diarrheal stool. A random-effects model was used to determine the pooled prevalence of <i>Aeromonas</i>. <b><i>Results:</i></b> Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of <i>Aeromonas</i> was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity (<i>I</i><sup>2</sup> = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of <i>Aeromonas</i> was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). <b><i>Conclusion:</i></b> The prevalence of <i>Aeromonas</i>-associated diarrhea in children in Asia estimated in the present study highlighted the high burden of <i>Aeromonas</i> in some parts of Asia.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Systematic Review and Meta-Analysis of <i>Aeromonas</i>-Associated Diarrhea Among Children in Asia.\",\"authors\":\"Hamid Sadeghi, Masoumeh Aslanimehr, Farhad Nikkhahi, Roya Safari, Majid Vafaie, Saeideh Gholamzadeh Khoei\",\"doi\":\"10.1089/sur.2024.090\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Background:</i></b> Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. <i>Aeromonas</i> is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of <i>Aeromonas</i> as an agent in the causation of diarrhea in Asian children. <b><i>Methods:</i></b> We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found <i>Aeromonas</i> in diarrheal stool. A random-effects model was used to determine the pooled prevalence of <i>Aeromonas</i>. <b><i>Results:</i></b> Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of <i>Aeromonas</i> was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity (<i>I</i><sup>2</sup> = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of <i>Aeromonas</i> was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). <b><i>Conclusion:</i></b> The prevalence of <i>Aeromonas</i>-associated diarrhea in children in Asia estimated in the present study highlighted the high burden of <i>Aeromonas</i> in some parts of Asia.</p>\",\"PeriodicalId\":22109,\"journal\":{\"name\":\"Surgical infections\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical infections\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/sur.2024.090\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/8/12 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical infections","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/sur.2024.090","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
摘要
背景:腹泻是发展中国家一个突出的公共卫生问题,导致儿童死亡率居高不下。社会人口特征和地理环境是导致儿童腹泻发病率上升的主要有效因素。气单胞菌是一种可引起痢疾和腹泻的被忽视的有机体。本系统综述和荟萃分析的目的是确定亚洲儿童腹泻的病原体--气单胞菌的流行情况。方法:我们使用 Web of Science、PubMed、Wiley Online Library、Science Direct 和 Google Scholar 对 2000 年 1 月至 2023 年 2 月间发表的同行评审文章进行了系统回顾。我们考虑了在腹泻粪便中发现气单胞菌的研究。我们采用随机效应模型来确定气单胞菌的总体流行率。结果:我们搜索到了 2,057 篇文章,其中来自 7 个亚洲国家的 17 篇文章被纳入系统综述。汇总的气单胞菌感染率为 4.5%(95% 置信区间 [CI]:2.9%-6.8%),存在异质性(I2 = 96.85;P < 0.001)。贫困人口多的地区(12.2%;95% CI:5.8%-24%)和中低收入国家(5.0%;95% CI:2.7%-9.0%)的发病率更高。此外,南亚(10.0%;95% CI:5.6%-17.2%)、印度(12.9%;95% CI:6.8%-23%)和露天排便率为 5%-25%的国家(11.3%;95% CI:6.3%-19.2%)的气单胞菌感染率较高。结论本研究估计的亚洲儿童与气单胞菌相关的腹泻发病率突出表明了气单胞菌在亚洲某些地区的高负担。
A Systematic Review and Meta-Analysis of Aeromonas-Associated Diarrhea Among Children in Asia.
Background: Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. Aeromonas is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of Aeromonas as an agent in the causation of diarrhea in Asian children. Methods: We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found Aeromonas in diarrheal stool. A random-effects model was used to determine the pooled prevalence of Aeromonas. Results: Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of Aeromonas was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity (I2 = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of Aeromonas was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). Conclusion: The prevalence of Aeromonas-associated diarrhea in children in Asia estimated in the present study highlighted the high burden of Aeromonas in some parts of Asia.
期刊介绍:
Surgical Infections provides comprehensive and authoritative information on the biology, prevention, and management of post-operative infections. Original articles cover the latest advancements, new therapeutic management strategies, and translational research that is being applied to improve clinical outcomes and successfully treat post-operative infections.
Surgical Infections coverage includes:
-Peritonitis and intra-abdominal infections-
Surgical site infections-
Pneumonia and other nosocomial infections-
Cellular and humoral immunity-
Biology of the host response-
Organ dysfunction syndromes-
Antibiotic use-
Resistant and opportunistic pathogens-
Epidemiology and prevention-
The operating room environment-
Diagnostic studies