超越常规:登革热导致横纹肌溶解症和 TMA 引起的 AKI 合并症的罕见病例报告。

IF 2.7 4区 医学 Q2 UROLOGY & NEPHROLOGY
Muhammad Junaid Tahir, Zoha Aftab, Zahid Nabi, Muhammad Ishaque
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引用次数: 0

摘要

登革热是全球最流行的节肢动物传播传染病。其临床表现从亚临床疾病到多器官衰竭不等。急性肾损伤(AKI)是其并发症之一,有多种不同的病原体。本文描述的患者出现了血栓性微血管病(TMA)和横纹肌溶解症,这是文献中从未报道过的并发症。他在一家初级保健医院被诊断为登革热,之后因发热和少尿转诊至我院。他的血液检查和肾活检结果显示,他合并有 TMA 和横纹肌溶解引起的 AKI。他在第一次接受血浆置换术后出现败血症,不得不停止治疗,并进一步接受透析和支持性护理。患者的恢复情况非常好,一个月后就恢复了肾功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Beyond the norm: a rare presentation of dengue fever resulting in combined rhabdomyolysis and TMA-induced AKI-a case report.

Beyond the norm: a rare presentation of dengue fever resulting in combined rhabdomyolysis and TMA-induced AKI-a case report.

Dengue is the most prevalent arthropod-transmitted infection worldwide. Its clinical presentation ranges from subclinical illness to multi-organ failure. Acute kidney injury (AKI) is one of its complications, having a number of different pathogeneses. The patient herein described presented with thrombotic microangiopathy (TMA) and rhabdomyolysis, a combination never previously reported in the literature. He was diagnosed with dengue at a primary care hospital, after which he was referred to us with fever and oliguria. His blood workup and kidney biopsy revealed a picture of combined TMA and rhabdomyolysis-induced AKI. He developed sepsis after his first session of plasmapheresis, that had to be discontinued and he was further managed with dialysis and supportive care. The patient showed remarkable recovery, regaining kidney function after one month.

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来源期刊
Journal of Nephrology
Journal of Nephrology 医学-泌尿学与肾脏学
CiteScore
5.60
自引率
5.90%
发文量
289
审稿时长
3-8 weeks
期刊介绍: Journal of Nephrology is a bimonthly journal that considers publication of peer reviewed original manuscripts dealing with both clinical and laboratory investigations of relevance to the broad fields of Nephrology, Dialysis and Transplantation. It is the Official Journal of the Italian Society of Nephrology (SIN).
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